Single-cell protein-mRNA correlation analysis enabled by multiplexed dual-analyte co-detection
Abstract We have investigated the correlation between proteins and mRNAs in single cells employing an integrated workflow for dual-analyte co-detection. This is achieved by combining the oligo extension reaction (OER), which converts protein levels to DNA levels, with reverse transcription for mRNA...
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Autores principales: | Haibiao Gong, Xiaohui Wang, Benjamin Liu, Stephane Boutet, Ilona Holcomb, Gajalakshmi Dakshinamoorthy, Aik Ooi, Chad Sanada, Gang Sun, Ramesh Ramakrishnan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/d53b4a806b534842a54ad55e4e3c21e5 |
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