MxB is an interferon-induced restriction factor of human herpesviruses

MxB is an interferon-induced GTPase that inhibits HIV replication. Here, Crameri et al. show that MxB restricts replication of herpesviruses by inhibiting delivery of incoming viral DNA into the nucleus, and this antiviral activity depends on MxB’s GTPase activity.

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Autores principales:	Michel Crameri, Michael Bauer, Nicole Caduff, Raphael Walker, Fiona Steiner, Francesca D. Franzoso, Cornelia Gujer, Karin Boucke, Talissa Kucera, Andrea Zbinden, Christian Münz, Cornel Fraefel, Urs F. Greber, Jovan Pavlovic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d543718eb03a4b21931bf3a778192211
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spelling	oai:doaj.org-article:d543718eb03a4b21931bf3a7781922112021-12-02T16:49:36ZMxB is an interferon-induced restriction factor of human herpesviruses10.1038/s41467-018-04379-22041-1723https://doaj.org/article/d543718eb03a4b21931bf3a7781922112018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04379-2https://doaj.org/toc/2041-1723MxB is an interferon-induced GTPase that inhibits HIV replication. Here, Crameri et al. show that MxB restricts replication of herpesviruses by inhibiting delivery of incoming viral DNA into the nucleus, and this antiviral activity depends on MxB’s GTPase activity.Michel CrameriMichael BauerNicole CaduffRaphael WalkerFiona SteinerFrancesca D. FranzosoCornelia GujerKarin BouckeTalissa KuceraAndrea ZbindenChristian MünzCornel FraefelUrs F. GreberJovan PavlovicNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michel Crameri Michael Bauer Nicole Caduff Raphael Walker Fiona Steiner Francesca D. Franzoso Cornelia Gujer Karin Boucke Talissa Kucera Andrea Zbinden Christian Münz Cornel Fraefel Urs F. Greber Jovan Pavlovic MxB is an interferon-induced restriction factor of human herpesviruses
description	MxB is an interferon-induced GTPase that inhibits HIV replication. Here, Crameri et al. show that MxB restricts replication of herpesviruses by inhibiting delivery of incoming viral DNA into the nucleus, and this antiviral activity depends on MxB’s GTPase activity.
format	article
author	Michel Crameri Michael Bauer Nicole Caduff Raphael Walker Fiona Steiner Francesca D. Franzoso Cornelia Gujer Karin Boucke Talissa Kucera Andrea Zbinden Christian Münz Cornel Fraefel Urs F. Greber Jovan Pavlovic
author_facet	Michel Crameri Michael Bauer Nicole Caduff Raphael Walker Fiona Steiner Francesca D. Franzoso Cornelia Gujer Karin Boucke Talissa Kucera Andrea Zbinden Christian Münz Cornel Fraefel Urs F. Greber Jovan Pavlovic
author_sort	Michel Crameri
title	MxB is an interferon-induced restriction factor of human herpesviruses
title_short	MxB is an interferon-induced restriction factor of human herpesviruses
title_full	MxB is an interferon-induced restriction factor of human herpesviruses
title_fullStr	MxB is an interferon-induced restriction factor of human herpesviruses
title_full_unstemmed	MxB is an interferon-induced restriction factor of human herpesviruses
title_sort	mxb is an interferon-induced restriction factor of human herpesviruses
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d543718eb03a4b21931bf3a778192211
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MxB is an interferon-induced restriction factor of human herpesviruses

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