Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature

Rheumatoid meningitis (RM) is a rare central nervous system (CNS) manifestation of rheumatoid arthritis (RA) with a wide spectrum of symptoms. We present a review of the literature with a rare illustrative case of a 61-year-old man with a history of seropositive rheumatoid arthritis (RA) who present...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sanyukta Joshi, Anna Masiak, Zbigniew Zdrojewski
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2020
Materias:	rheumatoid arthritis rheumatoid meningitis stroke-like symptoms central system involvement Medicine R
Acceso en línea:	https://doaj.org/article/d5477425fac64b73b9583e0294f2094b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d5477425fac64b73b9583e0294f2094b
record_format	dspace
spelling	oai:doaj.org-article:d5477425fac64b73b9583e0294f2094b2021-12-02T19:19:24ZRheumatoid arthritis with pachymeningitis – a case presentation and review of the literature0034-62332084-983410.5114/reum.2020.95368https://doaj.org/article/d5477425fac64b73b9583e0294f2094b2020-04-01T00:00:00Zhttps://www.termedia.pl/Rheumatoid-arthritis-with-pachymeningitis-a-case-presentation-and-review-of-the-literature,18,40683,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Rheumatoid meningitis (RM) is a rare central nervous system (CNS) manifestation of rheumatoid arthritis (RA) with a wide spectrum of symptoms. We present a review of the literature with a rare illustrative case of a 61-year-old man with a history of seropositive rheumatoid arthritis (RA) who presented headaches, stroke-like symptoms and seizures. MRI revealed the leptomeningeal enhancement in the right hemisphere. As cerebromeningeal fluid showed increased level of protein and was positive for Candida mannan, the initial clinical diagnosis was fungal meningitis. Despite the antifungal treatment the patient’s clinical condition did not improve. Detailed laboratory, radiologic and histopathological diagnostics enabled the diagnosis of RM. In conclusion is worth to highlight that presentation of RM is variable and complex, diagnosing it is a big dilemma which is why it must be considered in the differential in a patient with long-standing seropositive RA.Sanyukta JoshiAnna MasiakZbigniew ZdrojewskiTermedia Publishing Housearticlerheumatoid arthritis rheumatoid meningitis stroke-like symptoms central system involvementMedicineRENRheumatology, Vol 58, Iss 2, Pp 116-122 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	rheumatoid arthritis rheumatoid meningitis stroke-like symptoms central system involvement Medicine R
spellingShingle	rheumatoid arthritis rheumatoid meningitis stroke-like symptoms central system involvement Medicine R Sanyukta Joshi Anna Masiak Zbigniew Zdrojewski Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
description	Rheumatoid meningitis (RM) is a rare central nervous system (CNS) manifestation of rheumatoid arthritis (RA) with a wide spectrum of symptoms. We present a review of the literature with a rare illustrative case of a 61-year-old man with a history of seropositive rheumatoid arthritis (RA) who presented headaches, stroke-like symptoms and seizures. MRI revealed the leptomeningeal enhancement in the right hemisphere. As cerebromeningeal fluid showed increased level of protein and was positive for Candida mannan, the initial clinical diagnosis was fungal meningitis. Despite the antifungal treatment the patient’s clinical condition did not improve. Detailed laboratory, radiologic and histopathological diagnostics enabled the diagnosis of RM. In conclusion is worth to highlight that presentation of RM is variable and complex, diagnosing it is a big dilemma which is why it must be considered in the differential in a patient with long-standing seropositive RA.
format	article
author	Sanyukta Joshi Anna Masiak Zbigniew Zdrojewski
author_facet	Sanyukta Joshi Anna Masiak Zbigniew Zdrojewski
author_sort	Sanyukta Joshi
title	Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
title_short	Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
title_full	Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
title_fullStr	Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
title_full_unstemmed	Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
title_sort	rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature
publisher	Termedia Publishing House
publishDate	2020
url	https://doaj.org/article/d5477425fac64b73b9583e0294f2094b
work_keys_str_mv	AT sanyuktajoshi rheumatoidarthritiswithpachymeningitisacasepresentationandreviewoftheliterature AT annamasiak rheumatoidarthritiswithpachymeningitisacasepresentationandreviewoftheliterature AT zbigniewzdrojewski rheumatoidarthritiswithpachymeningitisacasepresentationandreviewoftheliterature
_version_	1718376882470125568

Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature

Ejemplares similares