Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension

Dorota PozarowskaDepartment of Ophthalmology, Medical University, Lublin, PolandAbstract: Glaucoma is one of the most common neuropathies of the optic nerve. An elevated intraocular pressure (IOP) is a well documented risk factor for the development and progression of this disease. Until now, IOP re...

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Autor principal:	Dorota Pozarowska
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/d548bce974a8471e9e05acfb59d8f20a
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spelling	oai:doaj.org-article:d548bce974a8471e9e05acfb59d8f20a2021-12-02T09:06:33ZSafety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension1177-54671177-5483https://doaj.org/article/d548bce974a8471e9e05acfb59d8f20a2010-10-01T00:00:00Zhttp://www.dovepress.com/safety-and-tolerability-of-tafluprost-in-treatment-of-elevated-intraoc-a5520https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Dorota PozarowskaDepartment of Ophthalmology, Medical University, Lublin, PolandAbstract: Glaucoma is one of the most common neuropathies of the optic nerve. An elevated intraocular pressure (IOP) is a well documented risk factor for the development and progression of this disease. Until now, IOP reduction is the only well documented successful method of glaucoma treatment. Among the many hypotensive drugs, prostaglandin analogs are proved to be the most potent antiglaucoma agents, with very few systemic side effects. A new prostanoid FP receptor analog, tafluprost, has been introduced into the medical treatment of glaucoma and ocular hypertension. Many studies have shown that it is an efficient IOP-lowering drug, and that it is safe and well tolerated. A preservative-free tafluprost formulation is as potent as a preserved one, but it has fewer and milder toxic effects on the eye.Keywords: tafluprost, prostaglandins, pharmacokinetics, safety, toxic effects, preservatives Dorota PozarowskaDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 1229-1236 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Dorota Pozarowska Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
description	Dorota PozarowskaDepartment of Ophthalmology, Medical University, Lublin, PolandAbstract: Glaucoma is one of the most common neuropathies of the optic nerve. An elevated intraocular pressure (IOP) is a well documented risk factor for the development and progression of this disease. Until now, IOP reduction is the only well documented successful method of glaucoma treatment. Among the many hypotensive drugs, prostaglandin analogs are proved to be the most potent antiglaucoma agents, with very few systemic side effects. A new prostanoid FP receptor analog, tafluprost, has been introduced into the medical treatment of glaucoma and ocular hypertension. Many studies have shown that it is an efficient IOP-lowering drug, and that it is safe and well tolerated. A preservative-free tafluprost formulation is as potent as a preserved one, but it has fewer and milder toxic effects on the eye.Keywords: tafluprost, prostaglandins, pharmacokinetics, safety, toxic effects, preservatives
format	article
author	Dorota Pozarowska
author_facet	Dorota Pozarowska
author_sort	Dorota Pozarowska
title	Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_short	Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_full	Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_fullStr	Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_full_unstemmed	Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_sort	safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/d548bce974a8471e9e05acfb59d8f20a
work_keys_str_mv	AT dorotapozarowska safetyandtolerabilityoftafluprostintreatmentofelevatedintraocularpressureinopenangleglaucomaandocularhypertension
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Safety and tolerability of tafluprost in treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension

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