Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent.
Studies in diverse organisms have revealed a surprising depth to the evolutionary conservation of genetic modules. For example, a systematic analysis of such conserved modules has recently shown that genes in yeast that maintain cell walls have been repurposed in vertebrates to regulate vein and art...
Guardado en:
Autores principales: | Hye Ji Cha, Michelle Byrom, Paul E Mead, Andrew D Ellington, John B Wallingford, Edward M Marcotte |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/d54a379b43ab4f1ca5f3ee50970cc441 |
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