A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans.
The APOBEC3 deaminases are potent inhibitors of virus replication and barriers to cross-species transmission. For simian immunodeficiency virus (SIV) to transmit to a new primate host, as happened multiple times to seed the ongoing HIV-1 epidemic, the viral infectivity factor (Vif) must be capable o...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2020
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| Accès en ligne: | https://doaj.org/article/d550843508e54cdeb238ee8a7ee1d1a4 |
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