A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans.

The APOBEC3 deaminases are potent inhibitors of virus replication and barriers to cross-species transmission. For simian immunodeficiency virus (SIV) to transmit to a new primate host, as happened multiple times to seed the ongoing HIV-1 epidemic, the viral infectivity factor (Vif) must be capable o...

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Auteurs principaux:	Yusuke Nakano, Keisuke Yamamoto, Mahoko Takahashi Ueda, Andrew Soper, Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Ryuichi Kumata, Hirofumi Aso, Naoko Misawa, Shumpei Nagaoka, Soma Shimizu, Keito Mitsumune, Yusuke Kosugi, Guillermo Juarez-Fernandez, Jumpei Ito, So Nakagawa, Terumasa Ikeda, Yoshio Koyanagi, Reuben S Harris, Kei Sato
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2020
Sujets:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/d550843508e54cdeb238ee8a7ee1d1a4
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A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans.

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