Model-based understanding of single-cell CRISPR screening

Single-cell CRISPR screening combines pooled CRISPR screening with scRNA-seq analysis to expand the resolution power of genetic screening. Here, the authors develop MUSIC, a computational pipeline for analyzing single-cell CRISPR screening data.

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Detalles Bibliográficos
Autores principales: Bin Duan, Chi Zhou, Chengyu Zhu, Yifei Yu, Gaoyang Li, Shihua Zhang, Chao Zhang, Xiangyun Ye, Hanhui Ma, Shen Qu, Zhiyuan Zhang, Ping Wang, Shuyang Sun, Qi Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/d55325cc875f45339a237406f0ff60cf
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