Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).

The NATURE-HF registry was aimed to describe clinical epidemiology and 1-year outcomes of outpatients and inpatients with heart failure (HF). This is a prospective, multicenter, observational survey conducted in Tunisian Cardiology centers. A total of 2040 patients were included in the study. Of the...

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Autores principales:	Leila Abid, Salma Charfeddine, Ikram Kammoun, Manel Ben Halima, Hedi Ben Slima, Meriem Drissa, Khadija Mzoughi, Dorra Mbarek, Leila Riahi, Saoussen Antit, Afef Ben Halima, Wejdene Ouechtati, Emna Allouche, Mehdi Mechri, Chedi Youssfi, Ali Khorchani, Kais Sammoud, Khaled Zaouia, Rami Tlili, Sana Ouali, Faten Triki, Sonia Hamdi, Selim Boudich, Marwa Chebbi, Mouna Hentati, Amani Farah, Habib Triki, H Ghardallou, H Radoui, Sofien Zayed, F Azaiez, Fadoua Omri, Akram Zouari, Zine Ben Ali, A Najjar, Houssem Thabet, Mouna Chaker, Samar Mohammed, Abdelhamid Ben Jmaa, Haithem Tangour, Yassine Kammoun, Mahmoud Cheikh Bouhlel, S Azeiz, R Gtaief, S Mashki, Aymen Amri, Hela Naanea, Raoudha Othmani, Iheb Chahbani, Houcine Zargouni, Syrine Abid, Mokded Ayari, Ines Ben Ameur, Ali Guesmi, Nejeh Ben Halima, Habib Haouala, Wafa Fehri, Essia Boughzela, Lilia Zakhama, Soraya Ben Youssef, Wided Nasraoui, Rachid Boujneh, Nedia Barakett, Sondos Kraiem, Hbiba Drissa, Ali Ben Khalfalah, Habib Gamra, Salem Kachboura, Yosra Majdoub, Elifa Kanoun, Faiez Zannad, Sami Milouchi, Alexandre Mebaza, Samir Kammoun, Sami Mourali, Karima Hezbri, Faouzi Addad
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d55862d6dfb748f9974fbcdee4509451
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spelling	oai:doaj.org-article:d55862d6dfb748f9974fbcdee45094512021-11-25T06:19:06ZEpidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).1932-620310.1371/journal.pone.0251658https://doaj.org/article/d55862d6dfb748f9974fbcdee45094512021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251658https://doaj.org/toc/1932-6203The NATURE-HF registry was aimed to describe clinical epidemiology and 1-year outcomes of outpatients and inpatients with heart failure (HF). This is a prospective, multicenter, observational survey conducted in Tunisian Cardiology centers. A total of 2040 patients were included in the study. Of these, 1632 (80%) were outpatients with chronic HF (CHF). The mean hospital stay was 8.7 ± 8.2 days. The mortality rate during the initial hospitalization event for AHF was 7.4%. The all-cause 1-year mortality rate was 22.8% among AHF patients and 10.6% among CHF patients. Among CHF patients, the older age, diabetes, anemia, reduced EF, ischemic etiology, residual congestion and the absence of ACEI/ ARBs treatment were independent predictors of 1-year cumulative rates of rehospitalization and mortality. The female sex and the functional status were independent predictors of 1-year all-cause mortality and rehospitalization in AHF patients. This study confirmed that acute HF is still associated with a poor prognosis, while the mid-term outcomes in patients with chronic HF seems to be improved. Some differences across countries may be due to different clinical characteristics and differences in healthcare systems.Leila AbidSalma CharfeddineIkram KammounManel Ben HalimaHedi Ben SlimaMeriem DrissaKhadija MzoughiDorra MbarekLeila RiahiSaoussen AntitAfef Ben HalimaWejdene OuechtatiEmna AlloucheMehdi MechriChedi YoussfiAli KhorchaniKais SammoudKhaled ZaouiaRami TliliSana OualiFaten TrikiSonia HamdiSelim BoudichMarwa ChebbiMouna HentatiAmani FarahHabib TrikiH GhardallouH RadouiSofien ZayedF AzaiezFadoua OmriAkram ZouariZine Ben AliA NajjarHoussem ThabetMouna ChakerSamar MohammedAbdelhamid Ben JmaaHaithem TangourYassine KammounMahmoud Cheikh BouhlelS AzeizR GtaiefS MashkiAymen AmriHela NaaneaRaoudha OthmaniIheb ChahbaniHoucine ZargouniSyrine AbidMokded AyariInes Ben AmeurAli GuesmiNejeh Ben HalimaHabib HaoualaWafa FehriEssia BoughzelaLilia ZakhamaSoraya Ben YoussefWided NasraouiRachid BoujnehNedia BarakettSondos KraiemHbiba DrissaAli Ben KhalfalahHabib GamraSalem KachbouraYosra MajdoubElifa KanounFaiez ZannadSami MilouchiAlexandre MebazaSamir KammounSami MouraliKarima HezbriFaouzi AddadPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 5, p e0251658 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Leila Abid Salma Charfeddine Ikram Kammoun Manel Ben Halima Hedi Ben Slima Meriem Drissa Khadija Mzoughi Dorra Mbarek Leila Riahi Saoussen Antit Afef Ben Halima Wejdene Ouechtati Emna Allouche Mehdi Mechri Chedi Youssfi Ali Khorchani Kais Sammoud Khaled Zaouia Rami Tlili Sana Ouali Faten Triki Sonia Hamdi Selim Boudich Marwa Chebbi Mouna Hentati Amani Farah Habib Triki H Ghardallou H Radoui Sofien Zayed F Azaiez Fadoua Omri Akram Zouari Zine Ben Ali A Najjar Houssem Thabet Mouna Chaker Samar Mohammed Abdelhamid Ben Jmaa Haithem Tangour Yassine Kammoun Mahmoud Cheikh Bouhlel S Azeiz R Gtaief S Mashki Aymen Amri Hela Naanea Raoudha Othmani Iheb Chahbani Houcine Zargouni Syrine Abid Mokded Ayari Ines Ben Ameur Ali Guesmi Nejeh Ben Halima Habib Haouala Wafa Fehri Essia Boughzela Lilia Zakhama Soraya Ben Youssef Wided Nasraoui Rachid Boujneh Nedia Barakett Sondos Kraiem Hbiba Drissa Ali Ben Khalfalah Habib Gamra Salem Kachboura Yosra Majdoub Elifa Kanoun Faiez Zannad Sami Milouchi Alexandre Mebaza Samir Kammoun Sami Mourali Karima Hezbri Faouzi Addad Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).
description	The NATURE-HF registry was aimed to describe clinical epidemiology and 1-year outcomes of outpatients and inpatients with heart failure (HF). This is a prospective, multicenter, observational survey conducted in Tunisian Cardiology centers. A total of 2040 patients were included in the study. Of these, 1632 (80%) were outpatients with chronic HF (CHF). The mean hospital stay was 8.7 ± 8.2 days. The mortality rate during the initial hospitalization event for AHF was 7.4%. The all-cause 1-year mortality rate was 22.8% among AHF patients and 10.6% among CHF patients. Among CHF patients, the older age, diabetes, anemia, reduced EF, ischemic etiology, residual congestion and the absence of ACEI/ ARBs treatment were independent predictors of 1-year cumulative rates of rehospitalization and mortality. The female sex and the functional status were independent predictors of 1-year all-cause mortality and rehospitalization in AHF patients. This study confirmed that acute HF is still associated with a poor prognosis, while the mid-term outcomes in patients with chronic HF seems to be improved. Some differences across countries may be due to different clinical characteristics and differences in healthcare systems.
format	article
author	Leila Abid Salma Charfeddine Ikram Kammoun Manel Ben Halima Hedi Ben Slima Meriem Drissa Khadija Mzoughi Dorra Mbarek Leila Riahi Saoussen Antit Afef Ben Halima Wejdene Ouechtati Emna Allouche Mehdi Mechri Chedi Youssfi Ali Khorchani Kais Sammoud Khaled Zaouia Rami Tlili Sana Ouali Faten Triki Sonia Hamdi Selim Boudich Marwa Chebbi Mouna Hentati Amani Farah Habib Triki H Ghardallou H Radoui Sofien Zayed F Azaiez Fadoua Omri Akram Zouari Zine Ben Ali A Najjar Houssem Thabet Mouna Chaker Samar Mohammed Abdelhamid Ben Jmaa Haithem Tangour Yassine Kammoun Mahmoud Cheikh Bouhlel S Azeiz R Gtaief S Mashki Aymen Amri Hela Naanea Raoudha Othmani Iheb Chahbani Houcine Zargouni Syrine Abid Mokded Ayari Ines Ben Ameur Ali Guesmi Nejeh Ben Halima Habib Haouala Wafa Fehri Essia Boughzela Lilia Zakhama Soraya Ben Youssef Wided Nasraoui Rachid Boujneh Nedia Barakett Sondos Kraiem Hbiba Drissa Ali Ben Khalfalah Habib Gamra Salem Kachboura Yosra Majdoub Elifa Kanoun Faiez Zannad Sami Milouchi Alexandre Mebaza Samir Kammoun Sami Mourali Karima Hezbri Faouzi Addad
author_facet	Leila Abid Salma Charfeddine Ikram Kammoun Manel Ben Halima Hedi Ben Slima Meriem Drissa Khadija Mzoughi Dorra Mbarek Leila Riahi Saoussen Antit Afef Ben Halima Wejdene Ouechtati Emna Allouche Mehdi Mechri Chedi Youssfi Ali Khorchani Kais Sammoud Khaled Zaouia Rami Tlili Sana Ouali Faten Triki Sonia Hamdi Selim Boudich Marwa Chebbi Mouna Hentati Amani Farah Habib Triki H Ghardallou H Radoui Sofien Zayed F Azaiez Fadoua Omri Akram Zouari Zine Ben Ali A Najjar Houssem Thabet Mouna Chaker Samar Mohammed Abdelhamid Ben Jmaa Haithem Tangour Yassine Kammoun Mahmoud Cheikh Bouhlel S Azeiz R Gtaief S Mashki Aymen Amri Hela Naanea Raoudha Othmani Iheb Chahbani Houcine Zargouni Syrine Abid Mokded Ayari Ines Ben Ameur Ali Guesmi Nejeh Ben Halima Habib Haouala Wafa Fehri Essia Boughzela Lilia Zakhama Soraya Ben Youssef Wided Nasraoui Rachid Boujneh Nedia Barakett Sondos Kraiem Hbiba Drissa Ali Ben Khalfalah Habib Gamra Salem Kachboura Yosra Majdoub Elifa Kanoun Faiez Zannad Sami Milouchi Alexandre Mebaza Samir Kammoun Sami Mourali Karima Hezbri Faouzi Addad
author_sort	Leila Abid
title	Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).
title_short	Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).
title_full	Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).
title_fullStr	Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).
title_full_unstemmed	Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).
title_sort	epidemiology of heart failure and long-term follow-up outcomes in a north-african population: results from the national tunisian registry of heart failure (nature-hf).
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/d55862d6dfb748f9974fbcdee4509451
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Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF).

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