Both IRBIT and long-IRBIT bind to and coordinately regulate Cl−/HCO3 − exchanger AE2 activity through modulating the lysosomal degradation of AE2

Both IRBIT and long-IRBIT bind to and coordinately regulate Cl−/HCO3 − exchanger AE2 activity through modulating the lysosomal degradation of AE2

Abstract Anion exchanger 2 (AE2) plays crucial roles in regulating cell volume homeostasis and cell migration. We found that both IRBIT and Long-IRBIT (L-IRBIT) interact with anion exchanger 2 (AE2). The interaction occurred between the conserved AHCY-homologous domain of IRBIT/L-IRBIT and the N-ter...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ryo Itoh, Naoya Hatano, Momoko Murakami, Kosuke Mitsumori, Satoko Kawasaki, Tomoka Wakagi, Yoshino Kanzaki, Hiroyuki Kojima, Katsuhiro Kawaai, Katsuhiko Mikoshiba, Koichi Hamada, Akihiro Mizutani
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d559a802affd44caa044cb922f75ff21
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares