Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms

Epigenetic control of enhancers may contribute to neurological disease. Here the authors carry out genome-wide analysis of DNA methylation in neurons isolated postmortem from patients with Alzheimer’s disease.

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Autores principales:	Peipei Li, Lee Marshall, Gabriel Oh, Jennifer L. Jakubowski, Daniel Groot, Yu He, Ting Wang, Arturas Petronis, Viviane Labrie
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5670791e46748e5b81b102dfc4bd386
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spelling	oai:doaj.org-article:d5670791e46748e5b81b102dfc4bd3862021-12-02T16:57:50ZEpigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms10.1038/s41467-019-10101-72041-1723https://doaj.org/article/d5670791e46748e5b81b102dfc4bd3862019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10101-7https://doaj.org/toc/2041-1723Epigenetic control of enhancers may contribute to neurological disease. Here the authors carry out genome-wide analysis of DNA methylation in neurons isolated postmortem from patients with Alzheimer’s disease.Peipei LiLee MarshallGabriel OhJennifer L. JakubowskiDaniel GrootYu HeTing WangArturas PetronisViviane LabrieNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peipei Li Lee Marshall Gabriel Oh Jennifer L. Jakubowski Daniel Groot Yu He Ting Wang Arturas Petronis Viviane Labrie Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
description	Epigenetic control of enhancers may contribute to neurological disease. Here the authors carry out genome-wide analysis of DNA methylation in neurons isolated postmortem from patients with Alzheimer’s disease.
format	article
author	Peipei Li Lee Marshall Gabriel Oh Jennifer L. Jakubowski Daniel Groot Yu He Ting Wang Arturas Petronis Viviane Labrie
author_facet	Peipei Li Lee Marshall Gabriel Oh Jennifer L. Jakubowski Daniel Groot Yu He Ting Wang Arturas Petronis Viviane Labrie
author_sort	Peipei Li
title	Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
title_short	Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
title_full	Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
title_fullStr	Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
title_full_unstemmed	Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
title_sort	epigenetic dysregulation of enhancers in neurons is associated with alzheimer’s disease pathology and cognitive symptoms
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d5670791e46748e5b81b102dfc4bd386
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Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms

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