Toll-like receptor 4 knockout mice are protected against endoplasmic reticulum stress induced by a high-fat diet.

Toll-like receptor 4 knockout mice are protected against endoplasmic reticulum stress induced by a high-fat diet.

The purpose of this study was to investigate whether toll-like receptor 4 (TLR4) is implicated in the development of endoplasmic reticulum stress (ER stress) observed after a high-fat diet (HFD) in liver, skeletal muscle and adipose tissue. TLR4(-/-) and C57BL/6J wild-type mice (WT) were fed with ch...

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Autores principales: Nicolas Pierre, Louise Deldicque, Caroline Barbé, Damien Naslain, Patrice D Cani, Marc Francaux
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d571c57be9344477a87724e65751c369
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