A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation

The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promoting cellular rearrangements leading to an open tu...

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Autores principales:	M. Ilcim Thestrup, Sara Caviglia, Jordi Cayuso, Ronja L. S. Heyne, Racha Ahmad, Wolfgang Hofmeister, Letizia Satriano, David G. Wilkinson, Jesper B. Andersen, Elke A. Ober
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d573b8c9777949828bdc150f56bc1b0b
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spelling	oai:doaj.org-article:d573b8c9777949828bdc150f56bc1b0b2021-12-02T15:35:10ZA morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation10.1038/s41467-019-13149-72041-1723https://doaj.org/article/d573b8c9777949828bdc150f56bc1b0b2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13149-7https://doaj.org/toc/2041-1723The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promoting cellular rearrangements leading to an open tube.M. Ilcim ThestrupSara CavigliaJordi CayusoRonja L. S. HeyneRacha AhmadWolfgang HofmeisterLetizia SatrianoDavid G. WilkinsonJesper B. AndersenElke A. OberNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q M. Ilcim Thestrup Sara Caviglia Jordi Cayuso Ronja L. S. Heyne Racha Ahmad Wolfgang Hofmeister Letizia Satriano David G. Wilkinson Jesper B. Andersen Elke A. Ober A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
description	The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promoting cellular rearrangements leading to an open tube.
format	article
author	M. Ilcim Thestrup Sara Caviglia Jordi Cayuso Ronja L. S. Heyne Racha Ahmad Wolfgang Hofmeister Letizia Satriano David G. Wilkinson Jesper B. Andersen Elke A. Ober
author_facet	M. Ilcim Thestrup Sara Caviglia Jordi Cayuso Ronja L. S. Heyne Racha Ahmad Wolfgang Hofmeister Letizia Satriano David G. Wilkinson Jesper B. Andersen Elke A. Ober
author_sort	M. Ilcim Thestrup
title	A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
title_short	A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
title_full	A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
title_fullStr	A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
title_full_unstemmed	A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
title_sort	morphogenetic ephb/ephrinb code controls hepatopancreatic duct formation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d573b8c9777949828bdc150f56bc1b0b
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A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation

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