The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial

Background: Probiotics catch more attention as adjunctive periodontal therapy. This study was conducted to assess the benefit of locally delivered Lactobacillus reuteri (L. reuteri) probiotic as an adjunctive to scaling and root planing (SRP) in the treatment of chronic periodontitis clinically and...

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Autores principales:	Ghadeer Khalil Mohamed El-bagoory, Hoda Mohamed El-guindy, Malak Yousef Mohamed Shoukheba, Enas Arafa El-zamarany
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	lactobacillus reuteri periodontitis polymerase chain reaction probiotics root planing Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/d57648d67b14493581d422f1e3ed084c
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spelling	oai:doaj.org-article:d57648d67b14493581d422f1e3ed084c2021-11-12T10:23:42ZThe adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial0972-124X10.4103/jisp.jisp_114_21https://doaj.org/article/d57648d67b14493581d422f1e3ed084c2021-01-01T00:00:00Zhttp://www.jisponline.com/article.asp?issn=0972-124X;year=2021;volume=25;issue=6;spage=525;epage=531;aulast=El-bagooryhttps://doaj.org/toc/0972-124XBackground: Probiotics catch more attention as adjunctive periodontal therapy. This study was conducted to assess the benefit of locally delivered Lactobacillus reuteri (L. reuteri) probiotic as an adjunctive to scaling and root planing (SRP) in the treatment of chronic periodontitis clinically and microbiologically. Materials and Methods: Bacterial cultures and clinical evaluation were recorded in 20 sites of chronic periodontitis in 12 patients and followed up at 3 and 6 months from the start of intervention using clinical attachment level, probing pocket depth, plaque index (PI), bleeding on probing, and microbiologically for Porphyromonas gingivalis (P. gingivalis) load. Patients meeting the inclusion criteria were scheduled within 1 week for two sessions of SRP. After SRP, oral hygiene measures were reassured, and sites were divided randomly into two groups 10 sites each. Group I received SRP only, while Group II received SRP and subgingival delivery of 1 ml of probiotic L. reuteri suspension at baseline and 1, 2, and 4 weeks using a blunt syringe. A periodontal pack was applied after the placement of the drug. Results: We found noticeable variation between the two groups in all evaluation aspects at 3 and 6-month follow-up periods except PI at 6 months in which there was no significant difference between both groups. Conclusions: The results proved the antimicrobial benefit of L. reuteri probiotic as a promising adjunctive therapy in improving periodontal parameters. However, further long-term studies with large sample size are needed to evaluate the extent of the added value of L. reuteri suspension.Ghadeer Khalil Mohamed El-bagooryHoda Mohamed El-guindyMalak Yousef Mohamed ShoukhebaEnas Arafa El-zamaranyWolters Kluwer Medknow Publicationsarticle lactobacillus reuteri periodontitispolymerase chain reactionprobioticsroot planingDentistryRK1-715ENJournal of Indian Society of Periodontology, Vol 25, Iss 6, Pp 525-531 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	lactobacillus reuteri periodontitis polymerase chain reaction probiotics root planing Dentistry RK1-715
spellingShingle	lactobacillus reuteri periodontitis polymerase chain reaction probiotics root planing Dentistry RK1-715 Ghadeer Khalil Mohamed El-bagoory Hoda Mohamed El-guindy Malak Yousef Mohamed Shoukheba Enas Arafa El-zamarany The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial
description	Background: Probiotics catch more attention as adjunctive periodontal therapy. This study was conducted to assess the benefit of locally delivered Lactobacillus reuteri (L. reuteri) probiotic as an adjunctive to scaling and root planing (SRP) in the treatment of chronic periodontitis clinically and microbiologically. Materials and Methods: Bacterial cultures and clinical evaluation were recorded in 20 sites of chronic periodontitis in 12 patients and followed up at 3 and 6 months from the start of intervention using clinical attachment level, probing pocket depth, plaque index (PI), bleeding on probing, and microbiologically for Porphyromonas gingivalis (P. gingivalis) load. Patients meeting the inclusion criteria were scheduled within 1 week for two sessions of SRP. After SRP, oral hygiene measures were reassured, and sites were divided randomly into two groups 10 sites each. Group I received SRP only, while Group II received SRP and subgingival delivery of 1 ml of probiotic L. reuteri suspension at baseline and 1, 2, and 4 weeks using a blunt syringe. A periodontal pack was applied after the placement of the drug. Results: We found noticeable variation between the two groups in all evaluation aspects at 3 and 6-month follow-up periods except PI at 6 months in which there was no significant difference between both groups. Conclusions: The results proved the antimicrobial benefit of L. reuteri probiotic as a promising adjunctive therapy in improving periodontal parameters. However, further long-term studies with large sample size are needed to evaluate the extent of the added value of L. reuteri suspension.
format	article
author	Ghadeer Khalil Mohamed El-bagoory Hoda Mohamed El-guindy Malak Yousef Mohamed Shoukheba Enas Arafa El-zamarany
author_facet	Ghadeer Khalil Mohamed El-bagoory Hoda Mohamed El-guindy Malak Yousef Mohamed Shoukheba Enas Arafa El-zamarany
author_sort	Ghadeer Khalil Mohamed El-bagoory
title	The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial
title_short	The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial
title_full	The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial
title_fullStr	The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial
title_full_unstemmed	The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial
title_sort	adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: a randomized controlled clinical trial
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/d57648d67b14493581d422f1e3ed084c
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The adjunctive effect of probiotics to nonsurgical treatment of chronic periodontitis: A randomized controlled clinical trial

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