Prominent bone loss mediated by RANKL and IL-17 produced by CD4+ T cells in TallyHo/JngJ mice.

Prominent bone loss mediated by RANKL and IL-17 produced by CD4+ T cells in TallyHo/JngJ mice.

Increasing evidence that decreased bone density and increased rates of bone fracture are associated with abnormal metabolic states such as hyperglycemia and insulin resistance indicates that diabetes is a risk factor for osteoporosis. In this study, we observed that TallyHo/JngJ (TH) mice, a polygen...

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Autores principales: Hee Yeon Won, Jin-Ah Lee, Zong Sik Park, Jin Sook Song, Hee Yun Kim, Su-Min Jang, Sung-Eun Yoo, Youmi Rhee, Eun Sook Hwang, Myung Ae Bae
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d57b7c7e782d4236abdc3a4df0b782cb
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