Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation

Chitinase 3-like-3 (Chi3l3) is expressed in microglia, but its function is not clear. Here the authors show that Chi3l3 is expressed in the subventricular zone in mouse experimental immune encephalitis, which induces oligodendrogenesis.

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Autores principales: Sarah C. Starossom, Juliana Campo Garcia, Tim Woelfle, Silvina Romero-Suarez, Marta Olah, Fumihiro Watanabe, Li Cao, Ada Yeste, John J. Tukker, Francisco J. Quintana, Jaime Imitola, Franziska Witzel, Dietmar Schmitz, Markus Morkel, Friedemann Paul, Carmen Infante-Duarte, Samia J. Khoury
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d57c2e0f41e642329b95d8514af6f963
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spelling oai:doaj.org-article:d57c2e0f41e642329b95d8514af6f9632021-12-02T16:57:06ZChi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation10.1038/s41467-018-08140-72041-1723https://doaj.org/article/d57c2e0f41e642329b95d8514af6f9632019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08140-7https://doaj.org/toc/2041-1723Chitinase 3-like-3 (Chi3l3) is expressed in microglia, but its function is not clear. Here the authors show that Chi3l3 is expressed in the subventricular zone in mouse experimental immune encephalitis, which induces oligodendrogenesis.Sarah C. StarossomJuliana Campo GarciaTim WoelfleSilvina Romero-SuarezMarta OlahFumihiro WatanabeLi CaoAda YesteJohn J. TukkerFrancisco J. QuintanaJaime ImitolaFranziska WitzelDietmar SchmitzMarkus MorkelFriedemann PaulCarmen Infante-DuarteSamia J. KhouryNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sarah C. Starossom
Juliana Campo Garcia
Tim Woelfle
Silvina Romero-Suarez
Marta Olah
Fumihiro Watanabe
Li Cao
Ada Yeste
John J. Tukker
Francisco J. Quintana
Jaime Imitola
Franziska Witzel
Dietmar Schmitz
Markus Morkel
Friedemann Paul
Carmen Infante-Duarte
Samia J. Khoury
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
description Chitinase 3-like-3 (Chi3l3) is expressed in microglia, but its function is not clear. Here the authors show that Chi3l3 is expressed in the subventricular zone in mouse experimental immune encephalitis, which induces oligodendrogenesis.
format article
author Sarah C. Starossom
Juliana Campo Garcia
Tim Woelfle
Silvina Romero-Suarez
Marta Olah
Fumihiro Watanabe
Li Cao
Ada Yeste
John J. Tukker
Francisco J. Quintana
Jaime Imitola
Franziska Witzel
Dietmar Schmitz
Markus Morkel
Friedemann Paul
Carmen Infante-Duarte
Samia J. Khoury
author_facet Sarah C. Starossom
Juliana Campo Garcia
Tim Woelfle
Silvina Romero-Suarez
Marta Olah
Fumihiro Watanabe
Li Cao
Ada Yeste
John J. Tukker
Francisco J. Quintana
Jaime Imitola
Franziska Witzel
Dietmar Schmitz
Markus Morkel
Friedemann Paul
Carmen Infante-Duarte
Samia J. Khoury
author_sort Sarah C. Starossom
title Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
title_short Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
title_full Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
title_fullStr Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
title_full_unstemmed Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
title_sort chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d57c2e0f41e642329b95d8514af6f963
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