Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations.

Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of transcripts (RNA-Seq) should offer several advantages...

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Bibliographic Details
Main Authors:	Brian B Tuch, Rebecca R Laborde, Xing Xu, Jian Gu, Christina B Chung, Cinna K Monighetti, Sarah J Stanley, Kerry D Olsen, Jan L Kasperbauer, Eric J Moore, Adam J Broomer, Ruoying Tan, Pius M Brzoska, Matthew W Muller, Asim S Siddiqui, Yan W Asmann, Yongming Sun, Scott Kuersten, Melissa A Barker, Francisco M De La Vega, David I Smith
Format:	article
Language:	EN
Published:	Public Library of Science (PLoS) 2010
Subjects:	Medicine R Science Q
Online Access:	https://doaj.org/article/d57e33fd8331426db6efefa7bbcd91fb
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Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations.

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