Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis

Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis

Abstract Neovascular age-related macular degeneration (nAMD) commonly causes vision loss from aberrant angiogenesis, termed choroidal neovascularization (CNV). Interleukin-6 (IL6) is a pro-inflammatory and pro-angiogenic cytokine that is correlated with AMD progression and nAMD activity. We hypothes...

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Autores principales: Steven Droho, Carla M. Cuda, Harris Perlman, Jeremy A. Lavine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d584da551c324321991bcae9b2906845
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