Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin

The bacterial type III secretion system of Gram-negative bacteria uses its core, the needle complex, to penetrate through the infected host cell membrane. Here authors show a near-atomic resolution structure of a needle complex which sheds light on the assembly and function of this nanomachine.

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Detalles Bibliográficos
Autores principales:	J. Hu, L. J. Worrall, C. Hong, M. Vuckovic, C. E. Atkinson, N. Caveney, Z. Yu, N. C. J. Strynadka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5926723fdcc407b9570656dc5261c3b
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spelling	oai:doaj.org-article:d5926723fdcc407b9570656dc5261c3b2021-12-02T15:34:47ZCryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin10.1038/s41467-018-06298-82041-1723https://doaj.org/article/d5926723fdcc407b9570656dc5261c3b2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06298-8https://doaj.org/toc/2041-1723The bacterial type III secretion system of Gram-negative bacteria uses its core, the needle complex, to penetrate through the infected host cell membrane. Here authors show a near-atomic resolution structure of a needle complex which sheds light on the assembly and function of this nanomachine.J. HuL. J. WorrallC. HongM. VuckovicC. E. AtkinsonN. CaveneyZ. YuN. C. J. StrynadkaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q J. Hu L. J. Worrall C. Hong M. Vuckovic C. E. Atkinson N. Caveney Z. Yu N. C. J. Strynadka Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
description	The bacterial type III secretion system of Gram-negative bacteria uses its core, the needle complex, to penetrate through the infected host cell membrane. Here authors show a near-atomic resolution structure of a needle complex which sheds light on the assembly and function of this nanomachine.
format	article
author	J. Hu L. J. Worrall C. Hong M. Vuckovic C. E. Atkinson N. Caveney Z. Yu N. C. J. Strynadka
author_facet	J. Hu L. J. Worrall C. Hong M. Vuckovic C. E. Atkinson N. Caveney Z. Yu N. C. J. Strynadka
author_sort	J. Hu
title	Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
title_short	Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
title_full	Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
title_fullStr	Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
title_full_unstemmed	Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
title_sort	cryo-em analysis of the t3s injectisome reveals the structure of the needle and open secretin
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d5926723fdcc407b9570656dc5261c3b
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Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin

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