Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China

Background: Vitamin D deficiency is prevalent globally and there is lack of evidence as to how 25(OH)D2 contributes to vitamin D status. The aim of this study was to describe vitamin D status and to assess the role of vitamin D2, a dietary vitamin D source, against the vitamin D status of children a...

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Autores principales:	Xuehong Pang, Zhenyu Yang, Jie Wang, Yifan Duan, Liyun Zhao, Dongmei Yu, Jianqiang Lai
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	China cross-sectional study preschool children 25-hydroxvitamin D2 25-hydroxvitamin D Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/d59db20219354d96ba7ef0b8cf6a123a
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spelling	oai:doaj.org-article:d59db20219354d96ba7ef0b8cf6a123a2021-11-25T18:37:01ZRelationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China10.3390/nu131141352072-6643https://doaj.org/article/d59db20219354d96ba7ef0b8cf6a123a2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4135https://doaj.org/toc/2072-6643Background: Vitamin D deficiency is prevalent globally and there is lack of evidence as to how 25(OH)D2 contributes to vitamin D status. The aim of this study was to describe vitamin D status and to assess the role of vitamin D2, a dietary vitamin D source, against the vitamin D status of children aged 3–5 years in China. Methods: Data were extracted from the Chinese National Nutrition and Health Surveillance (CNNHS) in 2013. The concentration of serum 25(OH)D2 and 25(OH)D3 was measured by using LC-MS/MS. Results: A total of 1435 subjects were enrolled and serum 25(OH)D were analyzed. The prevalence of total serum 25(OH)D < 30 nmol/L was 8.9%. Serum 25(OH)D2 was detected in 10.9% of the studied children. After adjusting for confounding factors, total 25(OH)D concentration was 8.48 nmol/L lower and odds ratio of vitamin D deficiency was 4.20 times (OR (95%CI): 4.20 (1.64, 10.77)) in children without 25(OH)D2 than those with 25(OH)D2 detected. Conclusions: Vitamin D deficiency was common among children aged 3–5 years in China. Vitamin D2 may play a role in preventing vitamin D deficiency in Chinese children aged 3–5 years.Xuehong PangZhenyu YangJie WangYifan DuanLiyun ZhaoDongmei YuJianqiang LaiMDPI AGarticleChinacross-sectional studypreschool children25-hydroxvitamin D225-hydroxvitamin DNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4135, p 4135 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	China cross-sectional study preschool children 25-hydroxvitamin D2 25-hydroxvitamin D Nutrition. Foods and food supply TX341-641
spellingShingle	China cross-sectional study preschool children 25-hydroxvitamin D2 25-hydroxvitamin D Nutrition. Foods and food supply TX341-641 Xuehong Pang Zhenyu Yang Jie Wang Yifan Duan Liyun Zhao Dongmei Yu Jianqiang Lai Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China
description	Background: Vitamin D deficiency is prevalent globally and there is lack of evidence as to how 25(OH)D2 contributes to vitamin D status. The aim of this study was to describe vitamin D status and to assess the role of vitamin D2, a dietary vitamin D source, against the vitamin D status of children aged 3–5 years in China. Methods: Data were extracted from the Chinese National Nutrition and Health Surveillance (CNNHS) in 2013. The concentration of serum 25(OH)D2 and 25(OH)D3 was measured by using LC-MS/MS. Results: A total of 1435 subjects were enrolled and serum 25(OH)D were analyzed. The prevalence of total serum 25(OH)D < 30 nmol/L was 8.9%. Serum 25(OH)D2 was detected in 10.9% of the studied children. After adjusting for confounding factors, total 25(OH)D concentration was 8.48 nmol/L lower and odds ratio of vitamin D deficiency was 4.20 times (OR (95%CI): 4.20 (1.64, 10.77)) in children without 25(OH)D2 than those with 25(OH)D2 detected. Conclusions: Vitamin D deficiency was common among children aged 3–5 years in China. Vitamin D2 may play a role in preventing vitamin D deficiency in Chinese children aged 3–5 years.
format	article
author	Xuehong Pang Zhenyu Yang Jie Wang Yifan Duan Liyun Zhao Dongmei Yu Jianqiang Lai
author_facet	Xuehong Pang Zhenyu Yang Jie Wang Yifan Duan Liyun Zhao Dongmei Yu Jianqiang Lai
author_sort	Xuehong Pang
title	Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China
title_short	Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China
title_full	Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China
title_fullStr	Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China
title_full_unstemmed	Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China
title_sort	relationship between serum 25oh-vitamin d2 level and vitamin d status of children aged 3–5 years in china
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/d59db20219354d96ba7ef0b8cf6a123a
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Relationship between Serum 25OH-Vitamin D2 Level and Vitamin D Status of Children Aged 3–5 Years in China

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