CagY-Dependent Regulation of Type IV Secretion in <named-content content-type="genus-species">Helicobacter pylori</named-content> Is Associated with Alterations in Integrin Binding

CagY-Dependent Regulation of Type IV Secretion in <named-content content-type="genus-species">Helicobacter pylori</named-content> Is Associated with Alterations in Integrin Binding

ABSTRACT Strains of Helicobacter pylori that cause ulcer or gastric cancer typically express a type IV secretion system (T4SS) encoded by the cag pathogenicity island (cagPAI). CagY is an ortholog of VirB10 that, unlike other VirB10 orthologs, has a large middle repeat region (MRR) with extensive re...

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Autores principales: Emma C. Skoog, Vasilios A. Morikis, Miriam E. Martin, Greg A. Foster, Lucy P. Cai, Lori M. Hansen, Beibei Li, Jennifer A. Gaddy, Scott I. Simon, Jay V. Solnick
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
CagA
CagY
Helicobacter pylori
integrin
pathogenicity island
type IV secretion system
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/d5a1ea5e1a5f4d1786af03886b030a49
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