The RNA-binding protein HuR is a negative regulator in adipogenesis

Human antigen R (HuR) is an RNA binding protein that promotes mRNA stability. Here the authors show that HuR represses adipogenesis in white and brown adipose tissue by stabilizing Insig1 and other targets.

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Autores principales:	Diana Teh Chee Siang, Yen Ching Lim, Aung Maung Maung Kyaw, Khaing Nwe Win, Sook Yoong Chia, Ufuk Degirmenci, Xiang Hu, Bryan C. Tan, Arcinas Camille Esther Walet, Lei Sun, Dan Xu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5a3ed7333c84e9d83c9d20cc549253a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:d5a3ed7333c84e9d83c9d20cc549253a2021-12-02T14:42:13ZThe RNA-binding protein HuR is a negative regulator in adipogenesis10.1038/s41467-019-14001-82041-1723https://doaj.org/article/d5a3ed7333c84e9d83c9d20cc549253a2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14001-8https://doaj.org/toc/2041-1723Human antigen R (HuR) is an RNA binding protein that promotes mRNA stability. Here the authors show that HuR represses adipogenesis in white and brown adipose tissue by stabilizing Insig1 and other targets.Diana Teh Chee SiangYen Ching LimAung Maung Maung KyawKhaing Nwe WinSook Yoong ChiaUfuk DegirmenciXiang HuBryan C. TanArcinas Camille Esther WaletLei SunDan XuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Diana Teh Chee Siang Yen Ching Lim Aung Maung Maung Kyaw Khaing Nwe Win Sook Yoong Chia Ufuk Degirmenci Xiang Hu Bryan C. Tan Arcinas Camille Esther Walet Lei Sun Dan Xu The RNA-binding protein HuR is a negative regulator in adipogenesis
description	Human antigen R (HuR) is an RNA binding protein that promotes mRNA stability. Here the authors show that HuR represses adipogenesis in white and brown adipose tissue by stabilizing Insig1 and other targets.
format	article
author	Diana Teh Chee Siang Yen Ching Lim Aung Maung Maung Kyaw Khaing Nwe Win Sook Yoong Chia Ufuk Degirmenci Xiang Hu Bryan C. Tan Arcinas Camille Esther Walet Lei Sun Dan Xu
author_facet	Diana Teh Chee Siang Yen Ching Lim Aung Maung Maung Kyaw Khaing Nwe Win Sook Yoong Chia Ufuk Degirmenci Xiang Hu Bryan C. Tan Arcinas Camille Esther Walet Lei Sun Dan Xu
author_sort	Diana Teh Chee Siang
title	The RNA-binding protein HuR is a negative regulator in adipogenesis
title_short	The RNA-binding protein HuR is a negative regulator in adipogenesis
title_full	The RNA-binding protein HuR is a negative regulator in adipogenesis
title_fullStr	The RNA-binding protein HuR is a negative regulator in adipogenesis
title_full_unstemmed	The RNA-binding protein HuR is a negative regulator in adipogenesis
title_sort	rna-binding protein hur is a negative regulator in adipogenesis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d5a3ed7333c84e9d83c9d20cc549253a
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The RNA-binding protein HuR is a negative regulator in adipogenesis

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