The RNA-binding protein HuR is a negative regulator in adipogenesis

Human antigen R (HuR) is an RNA binding protein that promotes mRNA stability. Here the authors show that HuR represses adipogenesis in white and brown adipose tissue by stabilizing Insig1 and other targets.

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Auteurs principaux: Diana Teh Chee Siang, Yen Ching Lim, Aung Maung Maung Kyaw, Khaing Nwe Win, Sook Yoong Chia, Ufuk Degirmenci, Xiang Hu, Bryan C. Tan, Arcinas Camille Esther Walet, Lei Sun, Dan Xu
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/d5a3ed7333c84e9d83c9d20cc549253a
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