Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration

Following epithelial-mesenchymal transition, avian trunk neural crest cell polarity determines directional migration but how this is established is unclear. Here, the authors find that the RhoGAP, Deleted in liver cancer 1, is asymmetrically localized in the cytoplasm, governing neural crest migrato...

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Autores principales:	Jessica Aijia Liu, Yanxia Rao, May Pui Lai Cheung, Man-Ning Hui, Ming-Hoi Wu, Lo-Kong Chan, Irene Oi-Lin Ng, Ben Niu, Kathryn S. E. Cheah, Rakesh Sharma, Louis Hodgson, Martin Cheung
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5afe614c7da4570bdef1328892dfbb0
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spelling	oai:doaj.org-article:d5afe614c7da4570bdef1328892dfbb02021-12-02T14:42:34ZAsymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration10.1038/s41467-017-01107-02041-1723https://doaj.org/article/d5afe614c7da4570bdef1328892dfbb02017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01107-0https://doaj.org/toc/2041-1723Following epithelial-mesenchymal transition, avian trunk neural crest cell polarity determines directional migration but how this is established is unclear. Here, the authors find that the RhoGAP, Deleted in liver cancer 1, is asymmetrically localized in the cytoplasm, governing neural crest migratory polarization.Jessica Aijia LiuYanxia RaoMay Pui Lai CheungMan-Ning HuiMing-Hoi WuLo-Kong ChanIrene Oi-Lin NgBen NiuKathryn S. E. CheahRakesh SharmaLouis HodgsonMartin CheungNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jessica Aijia Liu Yanxia Rao May Pui Lai Cheung Man-Ning Hui Ming-Hoi Wu Lo-Kong Chan Irene Oi-Lin Ng Ben Niu Kathryn S. E. Cheah Rakesh Sharma Louis Hodgson Martin Cheung Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
description	Following epithelial-mesenchymal transition, avian trunk neural crest cell polarity determines directional migration but how this is established is unclear. Here, the authors find that the RhoGAP, Deleted in liver cancer 1, is asymmetrically localized in the cytoplasm, governing neural crest migratory polarization.
format	article
author	Jessica Aijia Liu Yanxia Rao May Pui Lai Cheung Man-Ning Hui Ming-Hoi Wu Lo-Kong Chan Irene Oi-Lin Ng Ben Niu Kathryn S. E. Cheah Rakesh Sharma Louis Hodgson Martin Cheung
author_facet	Jessica Aijia Liu Yanxia Rao May Pui Lai Cheung Man-Ning Hui Ming-Hoi Wu Lo-Kong Chan Irene Oi-Lin Ng Ben Niu Kathryn S. E. Cheah Rakesh Sharma Louis Hodgson Martin Cheung
author_sort	Jessica Aijia Liu
title	Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
title_short	Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
title_full	Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
title_fullStr	Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
title_full_unstemmed	Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
title_sort	asymmetric localization of dlc1 defines avian trunk neural crest polarity for directional delamination and migration
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d5afe614c7da4570bdef1328892dfbb0
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Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration

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