Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of human ORFs and identification of human genes affecting viral titer.

The bottleneck in elucidating gene function through high-throughput gain-of-function genome screening is the limited availability of comprehensive libraries for gene overexpression. Lentiviral vectors are the most versatile and widely used vehicles for gene expression in mammalian cells. Lentiviral...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Dubravka Škalamera, Mareike Dahmer, Amy S Purdon, Benjamin M Wilson, Max V Ranall, Antje Blumenthal, Brian Gabrielli, Thomas J Gonda
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
R
Q
Acceso en línea:https://doaj.org/article/d5b5124f4ff94d909044fde07d4f2528
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares