Regeneration of severely damaged lungs using an interventional cross-circulation platform

Gastric aspiration severely injures donor lungs, frequently making them unacceptable for transplantation. Here the authors show that an interventional cross-circulation platform enables the regeneration of severely damaged lungs in a swine model of gastric aspiration injury.

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Autores principales: Brandon A. Guenthart, John D. O’Neill, Jinho Kim, Dawn Queen, Scott Chicotka, Kenmond Fung, Michael Simpson, Rachel Donocoff, Michael Salna, Charles C. Marboe, Katherine Cunningham, Susan P. Halligan, Holly M. Wobma, Ahmed E. Hozain, Alexander Romanov, Gordana Vunjak-Novakovic, Matthew Bacchetta
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d5b8dc81c66442c485f24ef1186a3a1f
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spelling oai:doaj.org-article:d5b8dc81c66442c485f24ef1186a3a1f2021-12-02T16:51:01ZRegeneration of severely damaged lungs using an interventional cross-circulation platform10.1038/s41467-019-09908-12041-1723https://doaj.org/article/d5b8dc81c66442c485f24ef1186a3a1f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09908-1https://doaj.org/toc/2041-1723Gastric aspiration severely injures donor lungs, frequently making them unacceptable for transplantation. Here the authors show that an interventional cross-circulation platform enables the regeneration of severely damaged lungs in a swine model of gastric aspiration injury.Brandon A. GuenthartJohn D. O’NeillJinho KimDawn QueenScott ChicotkaKenmond FungMichael SimpsonRachel DonocoffMichael SalnaCharles C. MarboeKatherine CunninghamSusan P. HalliganHolly M. WobmaAhmed E. HozainAlexander RomanovGordana Vunjak-NovakovicMatthew BacchettaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Brandon A. Guenthart
John D. O’Neill
Jinho Kim
Dawn Queen
Scott Chicotka
Kenmond Fung
Michael Simpson
Rachel Donocoff
Michael Salna
Charles C. Marboe
Katherine Cunningham
Susan P. Halligan
Holly M. Wobma
Ahmed E. Hozain
Alexander Romanov
Gordana Vunjak-Novakovic
Matthew Bacchetta
Regeneration of severely damaged lungs using an interventional cross-circulation platform
description Gastric aspiration severely injures donor lungs, frequently making them unacceptable for transplantation. Here the authors show that an interventional cross-circulation platform enables the regeneration of severely damaged lungs in a swine model of gastric aspiration injury.
format article
author Brandon A. Guenthart
John D. O’Neill
Jinho Kim
Dawn Queen
Scott Chicotka
Kenmond Fung
Michael Simpson
Rachel Donocoff
Michael Salna
Charles C. Marboe
Katherine Cunningham
Susan P. Halligan
Holly M. Wobma
Ahmed E. Hozain
Alexander Romanov
Gordana Vunjak-Novakovic
Matthew Bacchetta
author_facet Brandon A. Guenthart
John D. O’Neill
Jinho Kim
Dawn Queen
Scott Chicotka
Kenmond Fung
Michael Simpson
Rachel Donocoff
Michael Salna
Charles C. Marboe
Katherine Cunningham
Susan P. Halligan
Holly M. Wobma
Ahmed E. Hozain
Alexander Romanov
Gordana Vunjak-Novakovic
Matthew Bacchetta
author_sort Brandon A. Guenthart
title Regeneration of severely damaged lungs using an interventional cross-circulation platform
title_short Regeneration of severely damaged lungs using an interventional cross-circulation platform
title_full Regeneration of severely damaged lungs using an interventional cross-circulation platform
title_fullStr Regeneration of severely damaged lungs using an interventional cross-circulation platform
title_full_unstemmed Regeneration of severely damaged lungs using an interventional cross-circulation platform
title_sort regeneration of severely damaged lungs using an interventional cross-circulation platform
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d5b8dc81c66442c485f24ef1186a3a1f
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