Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors

COVID-19 has caused a severe global pandemic. Until now, there has been no simple and reliable system available in a lower-biosafety-grade laboratory for SARS-CoV-2 virologic research and inhibitor screening.

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Autores principales: Yuewen Luo, Fei Yu, Mo Zhou, Yang Liu, Baijin Xia, Xiantao Zhang, Jun Liu, Junsong Zhang, Yingying Du, Rong Li, Liyang Wu, Xu Zhang, Ting Pan, Deyin Guo, Tao Peng, Hui Zhang
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/d5c00aed9d414a1f927a51605da20f00
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Sumario:COVID-19 has caused a severe global pandemic. Until now, there has been no simple and reliable system available in a lower-biosafety-grade laboratory for SARS-CoV-2 virologic research and inhibitor screening.