Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors
COVID-19 has caused a severe global pandemic. Until now, there has been no simple and reliable system available in a lower-biosafety-grade laboratory for SARS-CoV-2 virologic research and inhibitor screening.
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American Society for Microbiology
2021
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oai:doaj.org-article:d5c00aed9d414a1f927a51605da20f002021-11-03T18:15:37ZEngineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors2161-21292150-751110.1128/mBio.02754-20https://doaj.org/article/d5c00aed9d414a1f927a51605da20f002021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02754-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 COVID-19 has caused a severe global pandemic. Until now, there has been no simple and reliable system available in a lower-biosafety-grade laboratory for SARS-CoV-2 virologic research and inhibitor screening.Yuewen LuoFei YuMo ZhouYang LiuBaijin XiaXiantao ZhangJun LiuJunsong ZhangYingying DuRong LiLiyang WuXu ZhangTing PanDeyin GuoTao PengHui ZhangAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Yuewen Luo Fei Yu Mo Zhou Yang Liu Baijin Xia Xiantao Zhang Jun Liu Junsong Zhang Yingying Du Rong Li Liyang Wu Xu Zhang Ting Pan Deyin Guo Tao Peng Hui Zhang Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors |
| description |
COVID-19 has caused a severe global pandemic. Until now, there has been no simple and reliable system available in a lower-biosafety-grade laboratory for SARS-CoV-2 virologic research and inhibitor screening. |
| format |
article |
| author |
Yuewen Luo Fei Yu Mo Zhou Yang Liu Baijin Xia Xiantao Zhang Jun Liu Junsong Zhang Yingying Du Rong Li Liyang Wu Xu Zhang Ting Pan Deyin Guo Tao Peng Hui Zhang |
| author_facet |
Yuewen Luo Fei Yu Mo Zhou Yang Liu Baijin Xia Xiantao Zhang Jun Liu Junsong Zhang Yingying Du Rong Li Liyang Wu Xu Zhang Ting Pan Deyin Guo Tao Peng Hui Zhang |
| author_sort |
Yuewen Luo |
| title |
Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors |
| title_short |
Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors |
| title_full |
Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors |
| title_fullStr |
Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors |
| title_full_unstemmed |
Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors |
| title_sort |
engineering a reliable and convenient sars-cov-2 replicon system for analysis of viral rna synthesis and screening of antiviral inhibitors |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/d5c00aed9d414a1f927a51605da20f00 |
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1718445486529052672 |