p70 Ribosomal Protein S6 Kinase Is a Checkpoint of Human Hepatic Stellate Cell Activation and Liver Fibrosis in MiceSummary

p70 Ribosomal Protein S6 Kinase Is a Checkpoint of Human Hepatic Stellate Cell Activation and Liver Fibrosis in MiceSummary

Background & Aims: Progression of chronic liver disease (CLD) to liver cirrhosis and liver cancer is a major global cause of morbidity and mortality. Treatment options capable of inhibiting progression of liver fibrosis when etiological treatment of CLD is not available or fails have yet to...

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Bibliographic Details
Main Authors: Florian P. Reiter, Liangtao Ye, Andrea Ofner, Tobias S. Schiergens, Andreas Ziesch, Lydia Brandl, Najib Ben Khaled, Simon Hohenester, Ralf Wimmer, Renate Artmann, Yulong He, Serene M.L. Lee, Doris Mayr, Changhua Zhang, Alexander L. Gerbes, Julia Mayerle, Gerald Denk, Enrico N. De Toni
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
Fibrosis
Cirrhosis
Chronic Liver Disease
Transforming Growth Factor-β
Platelet-Derived Growth Factor BB
Diseases of the digestive system. Gastroenterology
RC799-869
Online Access:https://doaj.org/article/d5c1e3f3e4744b00bcc68fbf2299c769
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https://doaj.org/article/d5c1e3f3e4744b00bcc68fbf2299c769

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