Discussions and perspectives regarding oxytocin as a biomarker in human investigations

This article introduces a review of research that has implemented oxytocin measurements in different fluids such as plasma, cerebrospinal fluid, urine and, mainly, saliva. The main purpose is to evaluate the level of evidence supporting the measurement of this biomarker implicated in a variety of ps...

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Autores principales:	Juan Carlos Caicedo Mera, Melissa Andrea Cárdenas Molano, Christian Camilo García López, Cristina Acevedo Triana, Jorge Martínez Cotrina
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Oxytocin Saliva ELISA RIA Social behavior Science (General) Q1-390 Social sciences (General) H1-99
Acceso en línea:	https://doaj.org/article/d5c7916cbe5e45f28f4887303cda41ec
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spelling	oai:doaj.org-article:d5c7916cbe5e45f28f4887303cda41ec2021-12-02T05:02:27ZDiscussions and perspectives regarding oxytocin as a biomarker in human investigations2405-844010.1016/j.heliyon.2021.e08289https://doaj.org/article/d5c7916cbe5e45f28f4887303cda41ec2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2405844021023926https://doaj.org/toc/2405-8440This article introduces a review of research that has implemented oxytocin measurements in different fluids such as plasma, cerebrospinal fluid, urine and, mainly, saliva. The main purpose is to evaluate the level of evidence supporting the measurement of this biomarker implicated in a variety of psychological and social processes. First, a review of the technical developments that allowed the characterization, function establishing, and central and peripheral levels of this hormone is proposed. Then, the article approaches the current discussions regarding the level of reliability of the laboratory techniques that enable the measurement of oxytocin, focusing mainly on the determination of its concentration in saliva through Enzyme-Linked Immunosorbent Assay (ELISA). Finally, research results, which have established the major physiological correlates of this hormone in fields such as social neuroscience and neuropsychology, are collected and discussed in terms of the hormone measurement methods that different authors have used. In this way, the article is expected to contribute to the panorama of debates and current perspectives regarding investigation involving this important biomarker.Juan Carlos Caicedo MeraMelissa Andrea Cárdenas MolanoChristian Camilo García LópezCristina Acevedo TrianaJorge Martínez CotrinaElsevierarticleOxytocinSalivaELISARIASocial behaviorScience (General)Q1-390Social sciences (General)H1-99ENHeliyon, Vol 7, Iss 11, Pp e08289- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Oxytocin Saliva ELISA RIA Social behavior Science (General) Q1-390 Social sciences (General) H1-99
spellingShingle	Oxytocin Saliva ELISA RIA Social behavior Science (General) Q1-390 Social sciences (General) H1-99 Juan Carlos Caicedo Mera Melissa Andrea Cárdenas Molano Christian Camilo García López Cristina Acevedo Triana Jorge Martínez Cotrina Discussions and perspectives regarding oxytocin as a biomarker in human investigations
description	This article introduces a review of research that has implemented oxytocin measurements in different fluids such as plasma, cerebrospinal fluid, urine and, mainly, saliva. The main purpose is to evaluate the level of evidence supporting the measurement of this biomarker implicated in a variety of psychological and social processes. First, a review of the technical developments that allowed the characterization, function establishing, and central and peripheral levels of this hormone is proposed. Then, the article approaches the current discussions regarding the level of reliability of the laboratory techniques that enable the measurement of oxytocin, focusing mainly on the determination of its concentration in saliva through Enzyme-Linked Immunosorbent Assay (ELISA). Finally, research results, which have established the major physiological correlates of this hormone in fields such as social neuroscience and neuropsychology, are collected and discussed in terms of the hormone measurement methods that different authors have used. In this way, the article is expected to contribute to the panorama of debates and current perspectives regarding investigation involving this important biomarker.
format	article
author	Juan Carlos Caicedo Mera Melissa Andrea Cárdenas Molano Christian Camilo García López Cristina Acevedo Triana Jorge Martínez Cotrina
author_facet	Juan Carlos Caicedo Mera Melissa Andrea Cárdenas Molano Christian Camilo García López Cristina Acevedo Triana Jorge Martínez Cotrina
author_sort	Juan Carlos Caicedo Mera
title	Discussions and perspectives regarding oxytocin as a biomarker in human investigations
title_short	Discussions and perspectives regarding oxytocin as a biomarker in human investigations
title_full	Discussions and perspectives regarding oxytocin as a biomarker in human investigations
title_fullStr	Discussions and perspectives regarding oxytocin as a biomarker in human investigations
title_full_unstemmed	Discussions and perspectives regarding oxytocin as a biomarker in human investigations
title_sort	discussions and perspectives regarding oxytocin as a biomarker in human investigations
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/d5c7916cbe5e45f28f4887303cda41ec
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Discussions and perspectives regarding oxytocin as a biomarker in human investigations

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