Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.

<h4>Background</h4>According to the World Health Organization, optimal adherence to Antiretroviral Therapy (ART) improves quality of life. Patients who use ART have varying characteristics in terms of where they live. The effect of place of residence on ART adherence is unclear in Ethiop...

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Autor principal: Robera Olana Fite
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Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/d5c93afc5b8247609020a71c506b0872
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spelling oai:doaj.org-article:d5c93afc5b8247609020a71c506b08722021-12-02T20:08:35ZAssociation between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.1932-620310.1371/journal.pone.0256948https://doaj.org/article/d5c93afc5b8247609020a71c506b08722021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0256948https://doaj.org/toc/1932-6203<h4>Background</h4>According to the World Health Organization, optimal adherence to Antiretroviral Therapy (ART) improves quality of life. Patients who use ART have varying characteristics in terms of where they live. The effect of place of residence on ART adherence is unclear in Ethiopia. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled association between place of residence and adherence to ART.<h4>Methods</h4>Articles were retrieved from PubMed, Scopus, African Journals Online (AJOL), Journal Storage (JSTOR), and Web of Science. The data was extracted using Microsoft Excel 2016 spreadsheet. Review Manager 5.3 and STATA version 14 were used for the analysis. The Cochrane Q statistic was used to assess between-study heterogeneity. I2 was used to quantify between-study heterogeneity. A weighted inverse variance random-effects model was used to calculate the pooled odds ratio with 95% confidence interval.<h4>Results</h4>Seven studies were included in this systematic review and meta-analysis. The Begg's test (Z = 0.15, P = 0.881) and Egger's test (t = 0.14, P = 0.894) revealed no evidence of publication bias. Urban residence was associated with an increased likelihood of good adherence (OR 2.07, 95%CI 1.22-3.51).<h4>Conclusions</h4>The study recommends that policy-makers should enact policies that increase access to ART services in a rural area in order to improve adherence. It is recommended that implementation studies be conducted in order to identify practical and affordable interventions.Robera Olana FitePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0256948 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Robera Olana Fite
Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.
description <h4>Background</h4>According to the World Health Organization, optimal adherence to Antiretroviral Therapy (ART) improves quality of life. Patients who use ART have varying characteristics in terms of where they live. The effect of place of residence on ART adherence is unclear in Ethiopia. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled association between place of residence and adherence to ART.<h4>Methods</h4>Articles were retrieved from PubMed, Scopus, African Journals Online (AJOL), Journal Storage (JSTOR), and Web of Science. The data was extracted using Microsoft Excel 2016 spreadsheet. Review Manager 5.3 and STATA version 14 were used for the analysis. The Cochrane Q statistic was used to assess between-study heterogeneity. I2 was used to quantify between-study heterogeneity. A weighted inverse variance random-effects model was used to calculate the pooled odds ratio with 95% confidence interval.<h4>Results</h4>Seven studies were included in this systematic review and meta-analysis. The Begg's test (Z = 0.15, P = 0.881) and Egger's test (t = 0.14, P = 0.894) revealed no evidence of publication bias. Urban residence was associated with an increased likelihood of good adherence (OR 2.07, 95%CI 1.22-3.51).<h4>Conclusions</h4>The study recommends that policy-makers should enact policies that increase access to ART services in a rural area in order to improve adherence. It is recommended that implementation studies be conducted in order to identify practical and affordable interventions.
format article
author Robera Olana Fite
author_facet Robera Olana Fite
author_sort Robera Olana Fite
title Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.
title_short Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.
title_full Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.
title_fullStr Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.
title_full_unstemmed Association between adherence to Antiretroviral Therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis.
title_sort association between adherence to antiretroviral therapy and place of residence among adult hiv infected patients in ethiopia: a systematic review and meta-analysis.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/d5c93afc5b8247609020a71c506b0872
work_keys_str_mv AT roberaolanafite associationbetweenadherencetoantiretroviraltherapyandplaceofresidenceamongadulthivinfectedpatientsinethiopiaasystematicreviewandmetaanalysis
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