Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis

Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis

Hyaluronan is a naturally occurring linear polysaccharide that together with collagens, enzymes, and glycoproteins forms the extracellular matrix. Here the authors show that adipose tissue overproduction of Hyaluronan reduces fat accumulation in mice fed high-fat diet and improves systemic glucose h...

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Autores principales: Yi Zhu, Na Li, Mingyang Huang, Mason Bartels, Sophie Dogné, Shangang Zhao, Xi Chen, Clair Crewe, Leon Straub, Lavanya Vishvanath, Zhuzhen Zhang, Mengle Shao, Yongjie Yang, Christy M. Gliniak, Ruth Gordillo, Gordon I. Smith, William L. Holland, Rana K. Gupta, Bingning Dong, Nathalie Caron, Yong Xu, Yucel Akgul, Samuel Klein, Philipp E. Scherer
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d5d6f30432264ee3a4a2783133e16a29
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spelling oai:doaj.org-article:d5d6f30432264ee3a4a2783133e16a292021-12-02T19:06:38ZAdipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis10.1038/s41467-021-25025-42041-1723https://doaj.org/article/d5d6f30432264ee3a4a2783133e16a292021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25025-4https://doaj.org/toc/2041-1723Hyaluronan is a naturally occurring linear polysaccharide that together with collagens, enzymes, and glycoproteins forms the extracellular matrix. Here the authors show that adipose tissue overproduction of Hyaluronan reduces fat accumulation in mice fed high-fat diet and improves systemic glucose homeostasis.Yi ZhuNa LiMingyang HuangMason BartelsSophie DognéShangang ZhaoXi ChenClair CreweLeon StraubLavanya VishvanathZhuzhen ZhangMengle ShaoYongjie YangChristy M. GliniakRuth GordilloGordon I. SmithWilliam L. HollandRana K. GuptaBingning DongNathalie CaronYong XuYucel AkgulSamuel KleinPhilipp E. SchererNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yi Zhu
Na Li
Mingyang Huang
Mason Bartels
Sophie Dogné
Shangang Zhao
Xi Chen
Clair Crewe
Leon Straub
Lavanya Vishvanath
Zhuzhen Zhang
Mengle Shao
Yongjie Yang
Christy M. Gliniak
Ruth Gordillo
Gordon I. Smith
William L. Holland
Rana K. Gupta
Bingning Dong
Nathalie Caron
Yong Xu
Yucel Akgul
Samuel Klein
Philipp E. Scherer
Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
description Hyaluronan is a naturally occurring linear polysaccharide that together with collagens, enzymes, and glycoproteins forms the extracellular matrix. Here the authors show that adipose tissue overproduction of Hyaluronan reduces fat accumulation in mice fed high-fat diet and improves systemic glucose homeostasis.
format article
author Yi Zhu
Na Li
Mingyang Huang
Mason Bartels
Sophie Dogné
Shangang Zhao
Xi Chen
Clair Crewe
Leon Straub
Lavanya Vishvanath
Zhuzhen Zhang
Mengle Shao
Yongjie Yang
Christy M. Gliniak
Ruth Gordillo
Gordon I. Smith
William L. Holland
Rana K. Gupta
Bingning Dong
Nathalie Caron
Yong Xu
Yucel Akgul
Samuel Klein
Philipp E. Scherer
author_facet Yi Zhu
Na Li
Mingyang Huang
Mason Bartels
Sophie Dogné
Shangang Zhao
Xi Chen
Clair Crewe
Leon Straub
Lavanya Vishvanath
Zhuzhen Zhang
Mengle Shao
Yongjie Yang
Christy M. Gliniak
Ruth Gordillo
Gordon I. Smith
William L. Holland
Rana K. Gupta
Bingning Dong
Nathalie Caron
Yong Xu
Yucel Akgul
Samuel Klein
Philipp E. Scherer
author_sort Yi Zhu
title Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
title_short Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
title_full Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
title_fullStr Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
title_full_unstemmed Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
title_sort adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for cl 316,243-stimulated lipolysis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d5d6f30432264ee3a4a2783133e16a29
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