Functional annotation of rare structural variation in the human brain

Functional annotation of rare structural variation in the human brain

Structural variants (SVs) contribute to the genetic architecture of many brain-related disorders. Here, the authors integrate SV calls from genome sequencing (n = 755) with RNA-seq data (n = 629) from post-mortem dorsal lateral prefrontal cortex to annotate the gene regulatory effects of SVs in the ...

Full description

Saved in:
Bibliographic Details
Main Authors: Lide Han, Xuefang Zhao, Mary Lauren Benton, Thaneer Perumal, Ryan L. Collins, Gabriel E. Hoffman, Jessica S. Johnson, Laura Sloofman, Harold Z. Wang, Matthew R. Stone, CommonMind Consortium, Kristen J. Brennand, Harrison Brand, Solveig K. Sieberts, Stefano Marenco, Mette A. Peters, Barbara K. Lipska, Panos Roussos, John A. Capra, Michael Talkowski, Douglas M. Ruderfer
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
Q
Online Access:https://doaj.org/article/d5da8027a19c4487875263a8dbf5c81b
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/d5da8027a19c4487875263a8dbf5c81b

Similar Items