Functional annotation of rare structural variation in the human brain
Structural variants (SVs) contribute to the genetic architecture of many brain-related disorders. Here, the authors integrate SV calls from genome sequencing (n = 755) with RNA-seq data (n = 629) from post-mortem dorsal lateral prefrontal cortex to annotate the gene regulatory effects of SVs in the ...
Guardado en:
Autores principales: | Lide Han, Xuefang Zhao, Mary Lauren Benton, Thaneer Perumal, Ryan L. Collins, Gabriel E. Hoffman, Jessica S. Johnson, Laura Sloofman, Harold Z. Wang, Matthew R. Stone, CommonMind Consortium, Kristen J. Brennand, Harrison Brand, Solveig K. Sieberts, Stefano Marenco, Mette A. Peters, Barbara K. Lipska, Panos Roussos, John A. Capra, Michael Talkowski, Douglas M. Ruderfer |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d5da8027a19c4487875263a8dbf5c81b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains
por: Gabriel E. Hoffman, et al.
Publicado: (2017) -
What if it was easier to prevent schizophrenia than to treat it?
por: Kristen J. Brennand
Publicado: (2017) -
PATH-DEPENDENCY, INSTITUCIONES POLÍTICAS Y REFORMAS ELECTORALES EN PERSPECTIVA COMPARADA
por: MARENCO,ANDRÉ
Publicado: (2006) -
When Institutions Matter: CAPES and Political Science in Brazil
por: MARENCO,ANDRÉ
Publicado: (2015) -
Neufeind M., O'Reilly J., and Ranft F. (2018, eds.), Work in the Digital Age: Challenges of the Fourth Industrial Revolution, London: Rowman & Littlefield
por: Matteo Marenco
Publicado: (2019)