Syk facilitates phagosome-lysosome fusion by regulating actin-remodeling in complement-mediated phagocytosis
Abstract Effective phagocytosis is crucial for host defense against pathogens. Macrophages entrap pathogens into a phagosome and subsequently acidic lysosomes fuse to the phagosome. Previous studies showed the pivotal role of actin-remodeling mediated by phosphoinositide-related signaling in phagoso...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/d5dfff707a7f48d58d3fc7b9c6932ac2 |
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