Propagation of temporal and rate signals in cultured multilayer networks

The nature of the signals that propagate through feedforward networks is not well understood. Here, the authors combine microfabrication, multilayer cortical cultures, and optogenetic stimulation to show that NMDA-mediated synaptic current generates a sustained phase of activity that propagates firi...

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Autores principales:	Jérémie Barral, Xiao-Jing Wang, Alex D. Reyes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5e4b1225b22452ebff3e4d288959398
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id	oai:doaj.org-article:d5e4b1225b22452ebff3e4d288959398
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spelling	oai:doaj.org-article:d5e4b1225b22452ebff3e4d2889593982021-12-02T16:58:14ZPropagation of temporal and rate signals in cultured multilayer networks10.1038/s41467-019-11851-02041-1723https://doaj.org/article/d5e4b1225b22452ebff3e4d2889593982019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11851-0https://doaj.org/toc/2041-1723The nature of the signals that propagate through feedforward networks is not well understood. Here, the authors combine microfabrication, multilayer cortical cultures, and optogenetic stimulation to show that NMDA-mediated synaptic current generates a sustained phase of activity that propagates firing rate signals.Jérémie BarralXiao-Jing WangAlex D. ReyesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jérémie Barral Xiao-Jing Wang Alex D. Reyes Propagation of temporal and rate signals in cultured multilayer networks
description	The nature of the signals that propagate through feedforward networks is not well understood. Here, the authors combine microfabrication, multilayer cortical cultures, and optogenetic stimulation to show that NMDA-mediated synaptic current generates a sustained phase of activity that propagates firing rate signals.
format	article
author	Jérémie Barral Xiao-Jing Wang Alex D. Reyes
author_facet	Jérémie Barral Xiao-Jing Wang Alex D. Reyes
author_sort	Jérémie Barral
title	Propagation of temporal and rate signals in cultured multilayer networks
title_short	Propagation of temporal and rate signals in cultured multilayer networks
title_full	Propagation of temporal and rate signals in cultured multilayer networks
title_fullStr	Propagation of temporal and rate signals in cultured multilayer networks
title_full_unstemmed	Propagation of temporal and rate signals in cultured multilayer networks
title_sort	propagation of temporal and rate signals in cultured multilayer networks
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d5e4b1225b22452ebff3e4d288959398
work_keys_str_mv	AT jeremiebarral propagationoftemporalandratesignalsinculturedmultilayernetworks AT xiaojingwang propagationoftemporalandratesignalsinculturedmultilayernetworks AT alexdreyes propagationoftemporalandratesignalsinculturedmultilayernetworks
_version_	1718382358070034432

Propagation of temporal and rate signals in cultured multilayer networks

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