A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division
PKCε is known to exert a role in genome protection by directly phosphorylating and switching the specificity of Aurora B. Here the authors identify SERBP1 as a parallel mitotic PKCε substrate controlling translation and ensuring the integrity of chromosome segregation and successful cell division.
Guardado en:
Autores principales: | Silvia Martini, Khalil Davis, Rupert Faraway, Lisa Elze, Nicola Lockwood, Andrew Jones, Xiao Xie, Neil Q. McDonald, David J. Mann, Alan Armstrong, Jernej Ule, Peter J. Parker |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d5e625f8ebda47a580e2c0dff47b3aba |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Kinetics of PKCε activating and inhibiting llama single chain antibodies and their effect on PKCε translocation in HeLa cells.
por: Milla Summanen, et al.
Publicado: (2012) -
PKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation
por: Tao Chen, et al.
Publicado: (2017) -
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
por: Rongfeng Zhu, et al.
Publicado: (2021) -
Dataset of bond enthalpies (εAA, εAB, εBB) in 975 binary intermetallic compounds
por: Daniel Miracle, et al.
Publicado: (2021) -
A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption.
por: Ting Gang Chew, et al.
Publicado: (2013)