Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer

Guo, Zhang, Guo et al. investigate microbiome alterations in different molecular subtypes of PDAC and report that distinct signatures exist in basal-like tumours, characterized by an increase in certain bacteria, such as Acinetobacter, Pseudomonas and Sphingopyxis. The authors associate increases in...

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Autores principales:	Wei Guo, Yuchao Zhang, Shiwei Guo, Zi Mei, Huiping Liao, Hang Dong, Kai Wu, Haocheng Ye, Yuhang Zhang, Yufei Zhu, Jingyu Lang, Landian Hu, Gang Jin, Xiangyin Kong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/d5ec81554c404472bf4b22956bb380fa
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spelling	oai:doaj.org-article:d5ec81554c404472bf4b22956bb380fa2021-12-02T16:37:36ZTumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer10.1038/s42003-021-02557-52399-3642https://doaj.org/article/d5ec81554c404472bf4b22956bb380fa2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02557-5https://doaj.org/toc/2399-3642Guo, Zhang, Guo et al. investigate microbiome alterations in different molecular subtypes of PDAC and report that distinct signatures exist in basal-like tumours, characterized by an increase in certain bacteria, such as Acinetobacter, Pseudomonas and Sphingopyxis. The authors associate increases in these bacteria with increased inflammation and carcinogenic potential, as suggested by pathway analyses.Wei GuoYuchao ZhangShiwei GuoZi MeiHuiping LiaoHang DongKai WuHaocheng YeYuhang ZhangYufei ZhuJingyu LangLandian HuGang JinXiangyin KongNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Wei Guo Yuchao Zhang Shiwei Guo Zi Mei Huiping Liao Hang Dong Kai Wu Haocheng Ye Yuhang Zhang Yufei Zhu Jingyu Lang Landian Hu Gang Jin Xiangyin Kong Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
description	Guo, Zhang, Guo et al. investigate microbiome alterations in different molecular subtypes of PDAC and report that distinct signatures exist in basal-like tumours, characterized by an increase in certain bacteria, such as Acinetobacter, Pseudomonas and Sphingopyxis. The authors associate increases in these bacteria with increased inflammation and carcinogenic potential, as suggested by pathway analyses.
format	article
author	Wei Guo Yuchao Zhang Shiwei Guo Zi Mei Huiping Liao Hang Dong Kai Wu Haocheng Ye Yuhang Zhang Yufei Zhu Jingyu Lang Landian Hu Gang Jin Xiangyin Kong
author_facet	Wei Guo Yuchao Zhang Shiwei Guo Zi Mei Huiping Liao Hang Dong Kai Wu Haocheng Ye Yuhang Zhang Yufei Zhu Jingyu Lang Landian Hu Gang Jin Xiangyin Kong
author_sort	Wei Guo
title	Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
title_short	Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
title_full	Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
title_fullStr	Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
title_full_unstemmed	Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
title_sort	tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d5ec81554c404472bf4b22956bb380fa
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Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer

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