A CRISPR-Assisted Nonhomologous End-Joining Strategy for Efficient Genome Editing in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

Código QR

A CRISPR-Assisted Nonhomologous End-Joining Strategy for Efficient Genome Editing in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT New tools for genetic manipulation of Mycobacterium tuberculosis are needed for the development of new drug regimens and vaccines aimed at curing tuberculosis infections. Clustered regularly interspaced short palindromic repeat (CRISPR)–CRISPR-associated protein (Cas) systems generate a hig...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mei-Yi Yan, Si-Shang Li, Xin-Yuan Ding, Xiao-Peng Guo, Qi Jin, Yi-Cheng Sun
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	CRISPR-Cas system Mycobacterium marinum Mycobacterium smegmatis Mycobacterium tuberculosis genome editing nonhomologous end joining Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/d5efd17612704f668563a19bea374a8f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Development of a CRISPR-Cas9 System for Efficient Genome Editing of <named-content content-type="genus-species">Candida lusitaniae</named-content>
por: Emily L. Norton, et al.
Publicado: (2017)

Comparative Genomic Analysis of <italic toggle="yes">Mycobacteriaceae</italic> Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Complex
por: Anoop Singh, et al.
Publicado: (2021)

mRNA Degradation Rates Are Coupled to Metabolic Status in <named-content content-type="genus-species">Mycobacterium smegmatis</named-content>
por: Diego A. Vargas-Blanco, et al.
Publicado: (2019)

Heterologous Production of 1-Tuberculosinyladenosine in <named-content content-type="genus-species">Mycobacterium kansasii</named-content> Models Pathoevolution towards the Transcellular Lifestyle of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Marwan Ghanem, et al.
Publicado: (2020)

A Case of Hypercalcemia in an Immunocompetent Patient with Disseminated Mycobacterium marinum Infection with a Rain Barrel as the Most Likely Primary Source
por: Wendy Uijtendaal, et al.
Publicado: (2021)

A Novel Calcium Uptake Transporter of Uncharacterized P-Type ATPase Family Supplies Calcium for Cell Surface Integrity in <italic toggle="yes">Mycobacterium smegmatis</italic>
por: Hemant Kumar Gupta, et al.
Publicado: (2017)

Intracellular <named-content content-type="genus-species">Mycobacterium leprae</named-content> Utilizes Host Glucose as a Carbon Source in Schwann Cells
por: Khushboo Borah, et al.
Publicado: (2019)

Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F<sub>420</sub>-0 in Mycobacteria
por: Rhys Grinter, et al.
Publicado: (2020)

An Attenuated CRISPR-Cas System in <named-content content-type="genus-species">Enterococcus faecalis</named-content> Permits DNA Acquisition
por: Karthik Hullahalli, et al.
Publicado: (2018)

Global Assessment of <named-content content-type="genus-species">Mycobacterium avium</named-content> subsp. <italic toggle="yes">hominissuis</italic> Genetic Requirement for Growth and Virulence
por: Marte S. Dragset, et al.
Publicado: (2019)

Optimizing Systems for Cas9 Expression in <named-content content-type="genus-species">Toxoplasma gondii</named-content>
por: Benedikt M. Markus, et al.
Publicado: (2019)

Bazedoxifene Suppresses Intracellular <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Growth by Enhancing Autophagy
por: Qi Ouyang, et al.
Publicado: (2020)

Protospacer-Adjacent Motif Specificity during <named-content content-type="genus-species">Clostridioides difficile</named-content> Type I-B CRISPR-Cas Interference and Adaptation
por: Anna Maikova, et al.
Publicado: (2021)

Lactoferricin Peptides Increase Macrophages' Capacity To Kill <named-content content-type="genus-species">Mycobacterium avium</named-content>
por: Tânia Silva, et al.
Publicado: (2017)

Cytokinin Signaling in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Marie I. Samanovic, et al.
Publicado: (2018)

Successful treatment of refractory cutaneous infection caused by Mycobacterium marinum with a combined regimen containing amikacin
por: Huang Y, et al.
Publicado: (2012)

Bactericidal Disruption of Magnesium Metallostasis in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Is Counteracted by Mutations in the Metal Ion Transporter CorA
por: Landys Lopez Quezada, et al.
Publicado: (2019)

Screening <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector
por: Chelsea E. Stamm, et al.
Publicado: (2019)

<italic toggle="yes">In Vivo</italic> Targeting of <named-content content-type="genus-species">Clostridioides difficile</named-content> Using Phage-Delivered CRISPR-Cas3 Antimicrobials
por: Kurt Selle, et al.
Publicado: (2020)

Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Elliot W. Kim, et al.
Publicado: (2019)

Signatures of Selection at Drug Resistance Loci in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Tatum D. Mortimer, et al.
Publicado: (2018)

<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Rv0991c Is a Redox-Regulated Molecular Chaperone
por: Samuel H. Becker, et al.
Publicado: (2020)

Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Nutrient Auxotrophy
por: Catherine Vilchèze, et al.
Publicado: (2018)

Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Michelle M. Bellerose, et al.
Publicado: (2020)

Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> during Early Macrophage Infection
por: Michael Zimmermann, et al.
Publicado: (2017)

An Efficient, Rapid, and Recyclable System for CRISPR-Mediated Genome Editing in <named-content content-type="genus-species">Candida albicans</named-content>
por: Namkha Nguyen, et al.
Publicado: (2017)

Role of Premycofactocin Synthase in Growth, Microaerophilic Adaptation, and Metabolism of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Gopinath Krishnamoorthy, et al.
Publicado: (2021)

Dual β-Lactam Combinations Highly Active against <named-content content-type="genus-species">Mycobacterium abscessus</named-content> Complex <italic toggle="yes">In Vitro</italic>
por: R. Pandey, et al.
Publicado: (2019)

Micobacterias atípicas en cinco pacientes adultos sin evidencias de inmunosupresión: Construyendo una experiencia
por: Fica,Alberto, et al.
Publicado: (2015)

CRISPR/Cas9 Mutagenesis in <named-content content-type="genus-species">Phlebotomus papatasi</named-content>: the Immune Deficiency Pathway Impacts Vector Competence for <named-content content-type="genus-species">Leishmania major</named-content>
por: Isabelle Louradour, et al.
Publicado: (2019)

A CRISPR Interference System for Efficient and Rapid Gene Knockdown in <named-content content-type="genus-species">Caulobacter crescentus</named-content>
por: Mathilde Guzzo, et al.
Publicado: (2020)

A Simplified and Efficient Method for Himar-1 Transposon Sequencing in Bacteria, Demonstrated by Creation and Analysis of a Saturated Transposon-Mutant Library in <named-content content-type="genus-species">Mycobacterium abscessus</named-content>
por: Mark Foreman, et al.
Publicado: (2020)

<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response
por: Ekansh Mittal, et al.
Publicado: (2018)

Treatment of Virulent <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> and HIV Coinfected Macrophages with Gallium Nanoparticles Inhibits Pathogen Growth and Modulates Macrophage Cytokine Production
por: Seoung-ryoung Choi, et al.
Publicado: (2019)

CRISPR and KRAS: a match yet to be made
por: Guzide Bender, et al.
Publicado: (2021)

Historia de la escrófula: de la discrasia humoral a la consunción
por: Duarte G,Ignacio, et al.
Publicado: (2016)

Synergistic Lethality of a Binary Inhibitor of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> KasA
por: Pradeep Kumar, et al.
Publicado: (2018)

Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Pallavi Chandra, et al.
Publicado: (2020)

Novel Antimicrobials from Uncultured Bacteria Acting against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Jeffrey Quigley, et al.
Publicado: (2020)

CD157 Confers Host Resistance to <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production
por: Qianting Yang, et al.
Publicado: (2019)