On the transience or stability of subthreshold psychopathology

Abstract Symptoms of psychopathology lie on a continuum ranging from mental health to psychiatric disorders. Although much research has focused on progression along this continuum, for most individuals, subthreshold symptoms do not escalate into full-blown disorders. This study investigated how the...

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Autores principales:	Marieke J. Schreuder, Johanna T. W. Wigman, Robin N. Groen, Marieke Wichers, Catharina A. Hartman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d5fce9ffb25b4e9f91cca7304afc3ad3
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spelling	oai:doaj.org-article:d5fce9ffb25b4e9f91cca7304afc3ad32021-12-05T12:14:31ZOn the transience or stability of subthreshold psychopathology10.1038/s41598-021-02711-32045-2322https://doaj.org/article/d5fce9ffb25b4e9f91cca7304afc3ad32021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02711-3https://doaj.org/toc/2045-2322Abstract Symptoms of psychopathology lie on a continuum ranging from mental health to psychiatric disorders. Although much research has focused on progression along this continuum, for most individuals, subthreshold symptoms do not escalate into full-blown disorders. This study investigated how the stability of psychopathological symptoms (attractor strength) varies across severity levels (homebase). Data were retrieved from the TRAILS TRANS-ID study, where 122 at-risk young adults (mean age 23.6 years old, 57% males) monitored their mental states daily for a period of six months (± 183 observations per participant). We estimated each individual’s homebase and attractor strength using generalized additive mixed models. Regression analyses showed no association between homebases and attractor strengths (linear model: B = 0.02, p = 0.47, R2 < 0.01; polynomial model: B < 0.01, p = 0.61, R2 < 0.01). Sensitivity analyses where we (1) weighed estimates according to their uncertainty and (2) removed individuals with a DSM-5 diagnosis from the analyses did not change this finding. This suggests that stability is similar across severity levels, implying that subthreshold psychopathology may resemble a stable state rather than a transient intermediate between mental health and psychiatric disorder. Our study thus provides additional support for a dimensional view on psychopathology, which implies that symptoms differ in degree rather than kind.Marieke J. SchreuderJohanna T. W. WigmanRobin N. GroenMarieke WichersCatharina A. HartmanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marieke J. Schreuder Johanna T. W. Wigman Robin N. Groen Marieke Wichers Catharina A. Hartman On the transience or stability of subthreshold psychopathology
description	Abstract Symptoms of psychopathology lie on a continuum ranging from mental health to psychiatric disorders. Although much research has focused on progression along this continuum, for most individuals, subthreshold symptoms do not escalate into full-blown disorders. This study investigated how the stability of psychopathological symptoms (attractor strength) varies across severity levels (homebase). Data were retrieved from the TRAILS TRANS-ID study, where 122 at-risk young adults (mean age 23.6 years old, 57% males) monitored their mental states daily for a period of six months (± 183 observations per participant). We estimated each individual’s homebase and attractor strength using generalized additive mixed models. Regression analyses showed no association between homebases and attractor strengths (linear model: B = 0.02, p = 0.47, R2 < 0.01; polynomial model: B < 0.01, p = 0.61, R2 < 0.01). Sensitivity analyses where we (1) weighed estimates according to their uncertainty and (2) removed individuals with a DSM-5 diagnosis from the analyses did not change this finding. This suggests that stability is similar across severity levels, implying that subthreshold psychopathology may resemble a stable state rather than a transient intermediate between mental health and psychiatric disorder. Our study thus provides additional support for a dimensional view on psychopathology, which implies that symptoms differ in degree rather than kind.
format	article
author	Marieke J. Schreuder Johanna T. W. Wigman Robin N. Groen Marieke Wichers Catharina A. Hartman
author_facet	Marieke J. Schreuder Johanna T. W. Wigman Robin N. Groen Marieke Wichers Catharina A. Hartman
author_sort	Marieke J. Schreuder
title	On the transience or stability of subthreshold psychopathology
title_short	On the transience or stability of subthreshold psychopathology
title_full	On the transience or stability of subthreshold psychopathology
title_fullStr	On the transience or stability of subthreshold psychopathology
title_full_unstemmed	On the transience or stability of subthreshold psychopathology
title_sort	on the transience or stability of subthreshold psychopathology
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d5fce9ffb25b4e9f91cca7304afc3ad3
work_keys_str_mv	AT mariekejschreuder onthetransienceorstabilityofsubthresholdpsychopathology AT johannatwwigman onthetransienceorstabilityofsubthresholdpsychopathology AT robinngroen onthetransienceorstabilityofsubthresholdpsychopathology AT mariekewichers onthetransienceorstabilityofsubthresholdpsychopathology AT catharinaahartman onthetransienceorstabilityofsubthresholdpsychopathology
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On the transience or stability of subthreshold psychopathology

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