Lymphadenopathy after the third Covid-19 vaccine

Summary: Axillary lymphadenopathy ipsilateral to the vaccination site has been clinically and radiologically reported after administration of COVID-19 vaccines. This can be an important diagnostic dilemma, particularly in cancer patients who are being staged or re-staged, as this benign entity may m...

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Bibliographic Details
Main Authors: Can Özütemiz, David A. Potter, Ayça Özbek Özütemiz, Daniel Steinberger
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/d6019e48c91048eebe76bf854fbe65f2
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Summary:Summary: Axillary lymphadenopathy ipsilateral to the vaccination site has been clinically and radiologically reported after administration of COVID-19 vaccines. This can be an important diagnostic dilemma, particularly in cancer patients who are being staged or re-staged, as this benign entity may mimic metastasis, cause unnecessary biopsies and changes in therapy. Here we present a breast cancer patient and a patient with squamous cell carcinoma of the head and neck, who had already received the first two doses of mRNA type COVID-19 vaccines before, now presenting with new hypermetabolic reactive lymphadenopathy on FDG PET/CT after the third booster dose.