Neural processes in antecedent anxiety modulate risk-taking behavior

Abstract Though real-world decisions are often made in the shadow of economic uncertainties, work problems, relationship troubles, existential angst, etc., the neural processes involved in this common experience remain poorly understood. Here, we randomly assigned participants (N = 97) to either a p...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kyle Nash, Josh Leota, Alex Tran
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d602bcb5c7a04e17bba8ff4fdf3ebb44
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d602bcb5c7a04e17bba8ff4fdf3ebb44
record_format	dspace
spelling	oai:doaj.org-article:d602bcb5c7a04e17bba8ff4fdf3ebb442021-12-02T10:48:13ZNeural processes in antecedent anxiety modulate risk-taking behavior10.1038/s41598-021-82229-w2045-2322https://doaj.org/article/d602bcb5c7a04e17bba8ff4fdf3ebb442021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-82229-whttps://doaj.org/toc/2045-2322Abstract Though real-world decisions are often made in the shadow of economic uncertainties, work problems, relationship troubles, existential angst, etc., the neural processes involved in this common experience remain poorly understood. Here, we randomly assigned participants (N = 97) to either a poignant experience of forecasted economic anxiety or a no-anxiety control condition. Using electroencephalography (EEG), we then examined how source-localized, anxiety-specific neural activation modulated risky decision making and strategic behavior in the Balloon Analogue Risk Task (BART). Previous research demonstrates opposing effects of anxiety on risk-taking, leading to contrasting predictions. On the one hand, activity in the dorsomedial PFC/anterior cingulate cortex (ACC) and anterior insula, brain regions linked with anxiety and sensitivity to risk, should mediate the effect of economic anxiety on increased risk-averse decision-making. On the other hand, activation in the ventromedial PFC, a brain region important in emotion regulation and subjective valuation in decision-making, should mediate the effect of economic anxiety on increased risky decision-making. Results revealed evidence related to both predictions. Additionally, anxiety-specific activation in the dmPFC/ACC and the anterior insula were associated with disrupted learning across the task. These results shed light on the neurobiology of antecedent anxiety and risk-taking and provide potential insight into understanding how real-world anxieties can impact decision-making processes.Kyle NashJosh LeotaAlex TranNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kyle Nash Josh Leota Alex Tran Neural processes in antecedent anxiety modulate risk-taking behavior
description	Abstract Though real-world decisions are often made in the shadow of economic uncertainties, work problems, relationship troubles, existential angst, etc., the neural processes involved in this common experience remain poorly understood. Here, we randomly assigned participants (N = 97) to either a poignant experience of forecasted economic anxiety or a no-anxiety control condition. Using electroencephalography (EEG), we then examined how source-localized, anxiety-specific neural activation modulated risky decision making and strategic behavior in the Balloon Analogue Risk Task (BART). Previous research demonstrates opposing effects of anxiety on risk-taking, leading to contrasting predictions. On the one hand, activity in the dorsomedial PFC/anterior cingulate cortex (ACC) and anterior insula, brain regions linked with anxiety and sensitivity to risk, should mediate the effect of economic anxiety on increased risk-averse decision-making. On the other hand, activation in the ventromedial PFC, a brain region important in emotion regulation and subjective valuation in decision-making, should mediate the effect of economic anxiety on increased risky decision-making. Results revealed evidence related to both predictions. Additionally, anxiety-specific activation in the dmPFC/ACC and the anterior insula were associated with disrupted learning across the task. These results shed light on the neurobiology of antecedent anxiety and risk-taking and provide potential insight into understanding how real-world anxieties can impact decision-making processes.
format	article
author	Kyle Nash Josh Leota Alex Tran
author_facet	Kyle Nash Josh Leota Alex Tran
author_sort	Kyle Nash
title	Neural processes in antecedent anxiety modulate risk-taking behavior
title_short	Neural processes in antecedent anxiety modulate risk-taking behavior
title_full	Neural processes in antecedent anxiety modulate risk-taking behavior
title_fullStr	Neural processes in antecedent anxiety modulate risk-taking behavior
title_full_unstemmed	Neural processes in antecedent anxiety modulate risk-taking behavior
title_sort	neural processes in antecedent anxiety modulate risk-taking behavior
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d602bcb5c7a04e17bba8ff4fdf3ebb44
work_keys_str_mv	AT kylenash neuralprocessesinantecedentanxietymodulaterisktakingbehavior AT joshleota neuralprocessesinantecedentanxietymodulaterisktakingbehavior AT alextran neuralprocessesinantecedentanxietymodulaterisktakingbehavior
_version_	1718396676813619200

Neural processes in antecedent anxiety modulate risk-taking behavior

Ejemplares similares