Regorafenib in metastatic colorectal cancer: more data for clinical decisions
Regorafenib is a multiple kinase inhibitor. It influences/blocks angiogenesis (VEGFR1-3, TIE2), proliferation (KIT, RET, RAF-1, BRAF), metastatic activity (VEGFR2-3, PDGFR), tumor immunogenicity (CSF1R), tumor microenvironment (PDGFR-, PDGFR-, FGFR1-2). Regorafenib has several indications including...
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Auteurs principaux: | Vladislav V. Petkau, Alisa A. Karimova, Zinaida V. Akishina |
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Format: | article |
Langue: | RU |
Publié: |
IP Habib O.N.
2021
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Accès en ligne: | https://doaj.org/article/d60c0e70abad4938848b0986a5a6d701 |
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