TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM

High-throughput single particle cryo-EM, for instance in drug research, requires the automation of the single particle analysis workflow. Here, the authors present TranSPHIRE, a software package that allows the fully-automated, feedback-driven processing of cryo-EM datasets during data acquisition.

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Autores principales:	Markus Stabrin, Fabian Schoenfeld, Thorsten Wagner, Sabrina Pospich, Christos Gatsogiannis, Stefan Raunser
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d60f1db43f614ca5b692b67d9a2a71c0
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spelling	oai:doaj.org-article:d60f1db43f614ca5b692b67d9a2a71c02021-12-02T15:39:28ZTranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM10.1038/s41467-020-19513-22041-1723https://doaj.org/article/d60f1db43f614ca5b692b67d9a2a71c02020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19513-2https://doaj.org/toc/2041-1723High-throughput single particle cryo-EM, for instance in drug research, requires the automation of the single particle analysis workflow. Here, the authors present TranSPHIRE, a software package that allows the fully-automated, feedback-driven processing of cryo-EM datasets during data acquisition.Markus StabrinFabian SchoenfeldThorsten WagnerSabrina PospichChristos GatsogiannisStefan RaunserNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Markus Stabrin Fabian Schoenfeld Thorsten Wagner Sabrina Pospich Christos Gatsogiannis Stefan Raunser TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
description	High-throughput single particle cryo-EM, for instance in drug research, requires the automation of the single particle analysis workflow. Here, the authors present TranSPHIRE, a software package that allows the fully-automated, feedback-driven processing of cryo-EM datasets during data acquisition.
format	article
author	Markus Stabrin Fabian Schoenfeld Thorsten Wagner Sabrina Pospich Christos Gatsogiannis Stefan Raunser
author_facet	Markus Stabrin Fabian Schoenfeld Thorsten Wagner Sabrina Pospich Christos Gatsogiannis Stefan Raunser
author_sort	Markus Stabrin
title	TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
title_short	TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
title_full	TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
title_fullStr	TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
title_full_unstemmed	TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
title_sort	transphire: automated and feedback-optimized on-the-fly processing for cryo-em
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d60f1db43f614ca5b692b67d9a2a71c0
work_keys_str_mv	AT markusstabrin transphireautomatedandfeedbackoptimizedontheflyprocessingforcryoem AT fabianschoenfeld transphireautomatedandfeedbackoptimizedontheflyprocessingforcryoem AT thorstenwagner transphireautomatedandfeedbackoptimizedontheflyprocessingforcryoem AT sabrinapospich transphireautomatedandfeedbackoptimizedontheflyprocessingforcryoem AT christosgatsogiannis transphireautomatedandfeedbackoptimizedontheflyprocessingforcryoem AT stefanraunser transphireautomatedandfeedbackoptimizedontheflyprocessingforcryoem
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TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM

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