Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma

Juan Carlos Izquierdo,1,2 Natalia Agudelo,1 Bárbara Rubio,1 Jorge Camargo,1 Katia Ruiz-Montenegro,1 Consuelo Gajardo,1 Mirel Rincon1 1Research Department, Oftalmosalud Instituto de Ojos, Lima, Perú; 2Glaucoma Department, Oftalmosalud Instituto de Ojos, Lima, PerúCorr...

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Autores principales:	Izquierdo JC, Agudelo N, Rubio B, Camargo J, Ruiz-Montenegro K, Gajardo C, Rincon M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	micro-incisional glaucoma surgery glaucoma surgery migs trabecular meshwork Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/d6204a19593f4791afd1e68200c9ab43
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spelling	oai:doaj.org-article:d6204a19593f4791afd1e68200c9ab432021-12-02T11:55:28ZCombined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma1177-5483https://doaj.org/article/d6204a19593f4791afd1e68200c9ab432021-01-01T00:00:00Zhttps://www.dovepress.com/combined-phacoemulsification-and-360-degree-endocyclophotocoagulation--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Juan Carlos Izquierdo,1,2 Natalia Agudelo,1 Bárbara Rubio,1 Jorge Camargo,1 Katia Ruiz-Montenegro,1 Consuelo Gajardo,1 Mirel Rincon1 1Research Department, Oftalmosalud Instituto de Ojos, Lima, Perú; 2Glaucoma Department, Oftalmosalud Instituto de Ojos, Lima, PerúCorrespondence: Natalia AgudeloOftalmosalud Instituto de Ojos, Av. Javier Prado Este 1142, San Isidro, Lima 27, PeruTel +51 1-985148485Fax +51 1-970584766Email dranataliaagudelo@gmail.comPurpose: The present study aimed to compare the outcomes of combined phacoemulsification and 360-degree endocyclophotocoagulation with and without goniotomy using a Kahook Dual Blade in patients with glaucoma.Patients and Methods: We enrolled 37 patients, 21 of whom underwent combined phacoemulsification with 360-degree endocyclophotocoagulation and goniotomy using a Kahook Dual Blade (tri-modal therapy (T-MT) group). The remaining 16 patients underwent phacoemulsification with endocyclophotocoagulation (bi-modal therapy (B-MT) group). Visual acuity, intraocular pressure, and number of glaucoma medications were recorded before the study and postoperatively on the first day, at week 1, and at 1, 3, 6, 9, and 12 months. Surgical success was defined as an IOP ≤ 12 mmHg and ≥ 6 mmHg or an at least 20% reduction in IOP from baseline with (qualified success) or without medications (complete success).Results: Forty-nine eyes were included. Baseline mean IOP was 16.96± 3.66 mmHg and 15.64± 4.88 mmHg in the T-MT and B-MT groups (p=0.122), respectively. At the 12-month follow-up, mean IOP values were 11.44± 2.15 mmHg and 12.45± 1.90 mmHg (p=0.031) in the T-MT and B-MT groups, respectively. Complete success rates were 37% in the T-MT group and 31% in the B-MT group, while qualified success rates were 74% and 50%, respectively. Glaucoma medications decreased from 2.0± 1.4 to 0.8± 1.0 (p< 0.001) in the T-MT group and from 1.5± 1.3 to 1.0± 1.5 in the B-MT group (p=0.032). Similar improvements in visual acuity were observed in both groups. Complications were mild and resolved without intervention.Conclusion: The tri-modal treatment is safe and may be more effective in reducing IOP and glaucoma medication requirements than bi-modal treatment.Keywords: micro-incisional glaucoma surgery, glaucoma surgery, MIGS, trabecular meshworkIzquierdo JCAgudelo NRubio BCamargo JRuiz-Montenegro KGajardo CRincon MDove Medical Pressarticlemicro-incisional glaucoma surgeryglaucoma surgerymigstrabecular meshworkOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 11-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	micro-incisional glaucoma surgery glaucoma surgery migs trabecular meshwork Ophthalmology RE1-994
spellingShingle	micro-incisional glaucoma surgery glaucoma surgery migs trabecular meshwork Ophthalmology RE1-994 Izquierdo JC Agudelo N Rubio B Camargo J Ruiz-Montenegro K Gajardo C Rincon M Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
description	Juan Carlos Izquierdo,1,2 Natalia Agudelo,1 Bárbara Rubio,1 Jorge Camargo,1 Katia Ruiz-Montenegro,1 Consuelo Gajardo,1 Mirel Rincon1 1Research Department, Oftalmosalud Instituto de Ojos, Lima, Perú; 2Glaucoma Department, Oftalmosalud Instituto de Ojos, Lima, PerúCorrespondence: Natalia AgudeloOftalmosalud Instituto de Ojos, Av. Javier Prado Este 1142, San Isidro, Lima 27, PeruTel +51 1-985148485Fax +51 1-970584766Email dranataliaagudelo@gmail.comPurpose: The present study aimed to compare the outcomes of combined phacoemulsification and 360-degree endocyclophotocoagulation with and without goniotomy using a Kahook Dual Blade in patients with glaucoma.Patients and Methods: We enrolled 37 patients, 21 of whom underwent combined phacoemulsification with 360-degree endocyclophotocoagulation and goniotomy using a Kahook Dual Blade (tri-modal therapy (T-MT) group). The remaining 16 patients underwent phacoemulsification with endocyclophotocoagulation (bi-modal therapy (B-MT) group). Visual acuity, intraocular pressure, and number of glaucoma medications were recorded before the study and postoperatively on the first day, at week 1, and at 1, 3, 6, 9, and 12 months. Surgical success was defined as an IOP ≤ 12 mmHg and ≥ 6 mmHg or an at least 20% reduction in IOP from baseline with (qualified success) or without medications (complete success).Results: Forty-nine eyes were included. Baseline mean IOP was 16.96± 3.66 mmHg and 15.64± 4.88 mmHg in the T-MT and B-MT groups (p=0.122), respectively. At the 12-month follow-up, mean IOP values were 11.44± 2.15 mmHg and 12.45± 1.90 mmHg (p=0.031) in the T-MT and B-MT groups, respectively. Complete success rates were 37% in the T-MT group and 31% in the B-MT group, while qualified success rates were 74% and 50%, respectively. Glaucoma medications decreased from 2.0± 1.4 to 0.8± 1.0 (p< 0.001) in the T-MT group and from 1.5± 1.3 to 1.0± 1.5 in the B-MT group (p=0.032). Similar improvements in visual acuity were observed in both groups. Complications were mild and resolved without intervention.Conclusion: The tri-modal treatment is safe and may be more effective in reducing IOP and glaucoma medication requirements than bi-modal treatment.Keywords: micro-incisional glaucoma surgery, glaucoma surgery, MIGS, trabecular meshwork
format	article
author	Izquierdo JC Agudelo N Rubio B Camargo J Ruiz-Montenegro K Gajardo C Rincon M
author_facet	Izquierdo JC Agudelo N Rubio B Camargo J Ruiz-Montenegro K Gajardo C Rincon M
author_sort	Izquierdo JC
title	Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
title_short	Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
title_full	Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
title_fullStr	Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
title_full_unstemmed	Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
title_sort	combined phacoemulsification and 360-degree endocyclophotocoagulation with and without a kahook dual blade in patients with primary open-angle glaucoma
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/d6204a19593f4791afd1e68200c9ab43
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Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma

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