Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment

Abstract Inhibition of programmed cell death pathways is frequently observed in cancer cells where it functions to facilitate tumor progression. However, some proteins involved in the regulation of cell death function dichotomously to both promote and inhibit cell death depending on the cellular con...

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Auteurs principaux: Matyas Abel Tsegaye, Jianping He, Kyle McGeehan, Ireland M. Murphy, Mati Nemera, Zachary T. Schafer
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/d62654ece9dd4e54ab38c4da97e1c7b1
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