Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood

The activity of the RNA splicing factor MBNL1 is altered in myotonic dystrophy (DM) patients. Here the authors characterize the thymic phenotype of Mbnl1 knockout mice, including developmental defects, transcriptome changes, and RNA mis-splicing of transcripts encoding thymic transcription factors.

Guardado en:
Detalles Bibliográficos
Autores principales: Łukasz J. Sznajder, Marina M. Scotti, Jihae Shin, Katarzyna Taylor, Franjo Ivankovic, Curtis A. Nutter, Faaiq N. Aslam, S. H. Subramony, Laura P. W. Ranum, Maurice S. Swanson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/d633908c2a2e467aa55689a91243f33f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares