Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy

Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder are co-occurring neurodevelopmental conditions displaying strong, discordant polygenic associations with educational attainment. Here, the authors study genetic mechanisms underlying genome-wide correlation patterns across these t...

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Autores principales: Ellen Verhoef, Jakob Grove, Chin Yang Shapland, Ditte Demontis, Stephen Burgess, Dheeraj Rai, Anders D. Børglum, Beate St Pourcain
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d63e598c05ef4e98bf8c32fd0438a45c
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spelling oai:doaj.org-article:d63e598c05ef4e98bf8c32fd0438a45c2021-11-14T12:34:46ZDiscordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy10.1038/s41467-021-26755-12041-1723https://doaj.org/article/d63e598c05ef4e98bf8c32fd0438a45c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26755-1https://doaj.org/toc/2041-1723Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder are co-occurring neurodevelopmental conditions displaying strong, discordant polygenic associations with educational attainment. Here, the authors study genetic mechanisms underlying genome-wide correlation patterns across these traits.Ellen VerhoefJakob GroveChin Yang ShaplandDitte DemontisStephen BurgessDheeraj RaiAnders D. BørglumBeate St PourcainNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ellen Verhoef
Jakob Grove
Chin Yang Shapland
Ditte Demontis
Stephen Burgess
Dheeraj Rai
Anders D. Børglum
Beate St Pourcain
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
description Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder are co-occurring neurodevelopmental conditions displaying strong, discordant polygenic associations with educational attainment. Here, the authors study genetic mechanisms underlying genome-wide correlation patterns across these traits.
format article
author Ellen Verhoef
Jakob Grove
Chin Yang Shapland
Ditte Demontis
Stephen Burgess
Dheeraj Rai
Anders D. Børglum
Beate St Pourcain
author_facet Ellen Verhoef
Jakob Grove
Chin Yang Shapland
Ditte Demontis
Stephen Burgess
Dheeraj Rai
Anders D. Børglum
Beate St Pourcain
author_sort Ellen Verhoef
title Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
title_short Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
title_full Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
title_fullStr Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
title_full_unstemmed Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
title_sort discordant associations of educational attainment with asd and adhd implicate a polygenic form of pleiotropy
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d63e598c05ef4e98bf8c32fd0438a45c
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