Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder are co-occurring neurodevelopmental conditions displaying strong, discordant polygenic associations with educational attainment. Here, the authors study genetic mechanisms underlying genome-wide correlation patterns across these t...
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Nature Portfolio
2021
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oai:doaj.org-article:d63e598c05ef4e98bf8c32fd0438a45c2021-11-14T12:34:46ZDiscordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy10.1038/s41467-021-26755-12041-1723https://doaj.org/article/d63e598c05ef4e98bf8c32fd0438a45c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26755-1https://doaj.org/toc/2041-1723Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder are co-occurring neurodevelopmental conditions displaying strong, discordant polygenic associations with educational attainment. Here, the authors study genetic mechanisms underlying genome-wide correlation patterns across these traits.Ellen VerhoefJakob GroveChin Yang ShaplandDitte DemontisStephen BurgessDheeraj RaiAnders D. BørglumBeate St PourcainNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q |
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Science Q Ellen Verhoef Jakob Grove Chin Yang Shapland Ditte Demontis Stephen Burgess Dheeraj Rai Anders D. Børglum Beate St Pourcain Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy |
description |
Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder are co-occurring neurodevelopmental conditions displaying strong, discordant polygenic associations with educational attainment. Here, the authors study genetic mechanisms underlying genome-wide correlation patterns across these traits. |
format |
article |
author |
Ellen Verhoef Jakob Grove Chin Yang Shapland Ditte Demontis Stephen Burgess Dheeraj Rai Anders D. Børglum Beate St Pourcain |
author_facet |
Ellen Verhoef Jakob Grove Chin Yang Shapland Ditte Demontis Stephen Burgess Dheeraj Rai Anders D. Børglum Beate St Pourcain |
author_sort |
Ellen Verhoef |
title |
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy |
title_short |
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy |
title_full |
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy |
title_fullStr |
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy |
title_full_unstemmed |
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy |
title_sort |
discordant associations of educational attainment with asd and adhd implicate a polygenic form of pleiotropy |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/d63e598c05ef4e98bf8c32fd0438a45c |
work_keys_str_mv |
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