Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells

The authors reprogram chicken fibroblast cells to form primordial germ cells (PGCs) in one species (black feather Langshan chicken) and then show such PGCs can be transplanted and migrate into the genital ridge of another chicken species (White Plymouth Rock) to produce viable offspring with the Cha...

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Autores principales: Ruifeng Zhao, Qisheng Zuo, Xia Yuan, Kai Jin, Jing Jin, Ying Ding, Chen Zhang, Tingting Li, Jingyi Jiang, Jiancheng Li, Ming Zhang, Xiang Shi, Hongyan Sun, Yani Zhang, Qi Xu, Guobin Chang, Zhenhua Zhao, Bing Li, Xinsheng Wu, Yang Zhang, Jiuzhou Song, Guohong Chen, Bichun Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d63eb2eb8ba44c2f86c659030550d226
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Sumario:The authors reprogram chicken fibroblast cells to form primordial germ cells (PGCs) in one species (black feather Langshan chicken) and then show such PGCs can be transplanted and migrate into the genital ridge of another chicken species (White Plymouth Rock) to produce viable offspring with the Characteristics of donor.