Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications

Abstract Of recent, immense attention has been given to chitosan in the biomedical field due to its valuable biochemical and physiological properties. Traditionally, the chief source of chitosan is chitin from crab and shrimp shells. Chitin is also an important component of fish scales, insects and...

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Autores principales:	Kenneth Ssekatawa, Denis K. Byarugaba, Eddie M. Wampande, Tlou N. Moja, Edward Nxumalo, Malik Maaza, Juliet Sackey, Francis Ejobi, John Baptist Kirabira
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d65a7ee0ed4c4bf08531a14fee302d21
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spelling	oai:doaj.org-article:d65a7ee0ed4c4bf08531a14fee302d212021-12-02T12:11:40ZIsolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications10.1038/s41598-021-81880-72045-2322https://doaj.org/article/d65a7ee0ed4c4bf08531a14fee302d212021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81880-7https://doaj.org/toc/2045-2322Abstract Of recent, immense attention has been given to chitosan in the biomedical field due to its valuable biochemical and physiological properties. Traditionally, the chief source of chitosan is chitin from crab and shrimp shells. Chitin is also an important component of fish scales, insects and fungal cell walls. Thus, the aim of this study was to isolate and characterize chitosan from locally available material for potential use in the biomedical field. Chitosan ash and nitrogen contents ranged from 1.55 to 3.5% and 6.6 to 7.0% respectively. Molecular weight varied from 291 to 348KDa. FTIR spectra revealed high degree of similarity between locally isolated chitosan and commercial chitosan with DD ranging from 77.8 to 79.1%. XRD patterns exhibited peaks at 2θ values of 19.5° for both mushroom and banana weevil chitosan while Nile perch scales chitosan registered 3 peaks at 2θ angles of 12.3°, 20.1° and 21.3° comparable to the established commercial chitosan XRD pattern. Locally isolated chitosan exhibited antimicrobial activity at a very high concentration. Ash content, moisture content, DD, FTIR spectra and XRD patterns revealed that chitosan isolated from locally available materials has physiochemical properties comparable to conventional chitosan and therefore it can be used in the biomedical field.Kenneth SsekatawaDenis K. ByarugabaEddie M. WampandeTlou N. MojaEdward NxumaloMalik MaazaJuliet SackeyFrancis EjobiJohn Baptist KirabiraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kenneth Ssekatawa Denis K. Byarugaba Eddie M. Wampande Tlou N. Moja Edward Nxumalo Malik Maaza Juliet Sackey Francis Ejobi John Baptist Kirabira Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
description	Abstract Of recent, immense attention has been given to chitosan in the biomedical field due to its valuable biochemical and physiological properties. Traditionally, the chief source of chitosan is chitin from crab and shrimp shells. Chitin is also an important component of fish scales, insects and fungal cell walls. Thus, the aim of this study was to isolate and characterize chitosan from locally available material for potential use in the biomedical field. Chitosan ash and nitrogen contents ranged from 1.55 to 3.5% and 6.6 to 7.0% respectively. Molecular weight varied from 291 to 348KDa. FTIR spectra revealed high degree of similarity between locally isolated chitosan and commercial chitosan with DD ranging from 77.8 to 79.1%. XRD patterns exhibited peaks at 2θ values of 19.5° for both mushroom and banana weevil chitosan while Nile perch scales chitosan registered 3 peaks at 2θ angles of 12.3°, 20.1° and 21.3° comparable to the established commercial chitosan XRD pattern. Locally isolated chitosan exhibited antimicrobial activity at a very high concentration. Ash content, moisture content, DD, FTIR spectra and XRD patterns revealed that chitosan isolated from locally available materials has physiochemical properties comparable to conventional chitosan and therefore it can be used in the biomedical field.
format	article
author	Kenneth Ssekatawa Denis K. Byarugaba Eddie M. Wampande Tlou N. Moja Edward Nxumalo Malik Maaza Juliet Sackey Francis Ejobi John Baptist Kirabira
author_facet	Kenneth Ssekatawa Denis K. Byarugaba Eddie M. Wampande Tlou N. Moja Edward Nxumalo Malik Maaza Juliet Sackey Francis Ejobi John Baptist Kirabira
author_sort	Kenneth Ssekatawa
title	Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
title_short	Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
title_full	Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
title_fullStr	Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
title_full_unstemmed	Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
title_sort	isolation and characterization of chitosan from ugandan edible mushrooms, nile perch scales and banana weevils for biomedical applications
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d65a7ee0ed4c4bf08531a14fee302d21
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Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications

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